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    KRIT1 KRIT1 ankyrin repeat containing [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702623, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KRIT1provided by VGNC
    Official Full Name
    KRIT1 ankyrin repeat containingprovided by VGNC
    Primary source
    VGNC:VGNC:81629
    See related
    Ensembl:ENSMMUG00000014907
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KRIT1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (113892559..113939501)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (117464514..117512035, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene mitochondrial intermembrane space import and assembly protein 40 pseudogene Neighboring gene transmembrane BAX inhibitor motif containing 7 Neighboring gene ankyrin repeat and IBR domain containing 1 Neighboring gene uncharacterized LOC114676989 Neighboring gene leucine rich repeats and death domain containing 1 Neighboring gene cytochrome P450 family 51 subfamily A member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of establishment of cell polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    krev interaction trapped protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261769.1 → NP_001248698.1  krev interaction trapped protein 1

      See identical proteins and their annotated locations for NP_001248698.1

      Status: PROVISIONAL

      Source sequence(s)
      JV043862
      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Related
      ENSMMUP00000035055.2, ENSMMUT00000042053.3
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      113892559..113939501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015134210.2 → XP_014989696.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    2. XM_015134211.2 → XP_014989697.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    3. XM_028844877.1 → XP_028700710.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    4. XM_015134209.2 → XP_014989695.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    5. XM_015134221.2 → XP_014989707.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    6. XM_015134213.2 → XP_014989699.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    7. XM_015134215.2 → XP_014989701.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    8. XM_015134217.2 → XP_014989703.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    9. XM_015134218.2 → XP_014989704.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    10. XM_028844879.1 → XP_028700712.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    11. XM_015134219.2 → XP_014989705.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Related
      ENSMMUP00000019562.4, ENSMMUT00000020913.4
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    12. XM_028844878.1 → XP_028700711.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    13. XM_028844875.1 → XP_028700708.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Related
      ENSMMUP00000041492.1, ENSMMUT00000071192.2
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    14. XM_028844876.1 → XP_028700709.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    15. XM_028844880.1 → XP_028700713.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT

    16. XM_015134222.2 → XP_014989708.1  krev interaction trapped protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0D0, A0A1D5QWY1, F6TVZ5
      Related
      ENSMMUP00000052561.2, ENSMMUT00000067878.2
      Conserved Domains (5) summary
      smart00295
      Location:421 → 640
      B41; Band 4.1 homologues
      cd13197
      Location:636 → 735
      FERM_C_CCM1; FERM domain C-lobe of Cerebral cavernous malformation 1
      sd00045
      Location:291 → 318
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:292 → 386
      Ank_2; Ankyrin repeats (3 copies)
      pfam16705
      Location:30 → 198
      NUDIX_5; NUDIX, or N-terminal NPxY motif-rich, region of KRIT
    Nucleotide Protein
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