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    APAF1 apoptotic peptidase activating factor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694164, updated on 17-Aug-2024

    Summary

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    Official Symbol
    APAF1provided by VGNC
    Official Full Name
    apoptotic peptidase activating factor 1provided by VGNC
    Primary source
    VGNC:VGNC:69975
    See related
    Ensembl:ENSMMUG00000022404
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See APAF1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (98425143..98513830)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (98473384..98573411)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA53 Neighboring gene solute carrier family 25 member 3 Neighboring gene IKBKB interacting protein Neighboring gene probable ribosome biogenesis protein RLP24 pseudogene Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene uncharacterized LOC114671032

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of apoptosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    apoptotic protease-activating factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      98425143..98513830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152496.2 → XP_015007982.2  apoptotic protease-activating factor 1

      UniProtKB/TrEMBL
      G7N581
      Related
      ENSMMUP00000029484.4, ENSMMUT00000031512.4
      Conserved Domains (4) summary
      cd00200
      Location:607 → 910
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd08323
      Location:7 → 92
      CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
      sd00039
      Location:660 → 697
      7WD40; WD40 repeat [structural motif]
      pfam00931
      Location:129 → 414
      NB-ARC; NB-ARC domain

    RNA

    1. XR_003720926.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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    Research Materials