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    P4HA1 prolyl 4-hydroxylase subunit alpha 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707927, updated on 17-Aug-2024

    Summary

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    Official Symbol
    P4HA1provided by VGNC
    Official Full Name
    prolyl 4-hydroxylase subunit alpha 1provided by VGNC
    Primary source
    VGNC:VGNC:75741
    Locus tag
    EGK_19739
    See related
    Ensembl:ENSMMUG00000011274
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See P4HA1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (64640387..64727801)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (59229187..59316949)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 149 member B1 Neighboring gene eukaryotic initiation factor 4A-II-like Neighboring gene small nucleolar RNA SNORA11 Neighboring gene ecdysoneless cell cycle regulator Neighboring gene nudix hydrolase 13 Neighboring gene phospholipase A2 group XIIB Neighboring gene nucleophosmin pseudogene Neighboring gene oncoprotein induced transcript 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables L-ascorbic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables procollagen-proline 4-dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-proline hydroxylation to 4-hydroxy-L-proline IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prolyl 4-hydroxylase subunit alpha-1
    Names
    procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I
    XP_015002886.1
    XP_015002887.1
    XP_028682324.1
    XP_028682326.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      64640387..64727801
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015147400.2 → XP_015002886.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

      UniProtKB/TrEMBL
      A0A5S6RDC1, A0A8J8Y6S5, F6WHG3, G7N269, H9FV18
      Related
      ENSMMUP00000014772.4, ENSMMUT00000015768.4
      Conserved Domains (3) summary
      smart00702
      Location:345 → 518
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
      pfam07719
      Location:207 → 238
      TPR_2; Tetratricopeptide repeat
      pfam08336
      Location:24 → 153
      P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

    2. XM_015147401.2 → XP_015002887.1  prolyl 4-hydroxylase subunit alpha-1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QPK3, H9FV19, H9Z9F8
      Related
      ENSMMUP00000049980.2, ENSMMUT00000069254.2
      Conserved Domains (3) summary
      smart00702
      Location:345 → 518
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
      pfam07719
      Location:207 → 238
      TPR_2; Tetratricopeptide repeat
      pfam08336
      Location:24 → 153
      P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

    3. XM_028826493.1 → XP_028682326.1  prolyl 4-hydroxylase subunit alpha-1 isoform X4

      UniProtKB/TrEMBL
      H9FV18
      Conserved Domains (3) summary
      smart00702
      Location:258 → 431
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
      pfam07719
      Location:120 → 151
      TPR_2; Tetratricopeptide repeat
      pfam08336
      Location:1 → 66
      P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

    4. XM_028826491.1 → XP_028682324.1  prolyl 4-hydroxylase subunit alpha-1 isoform X3

      UniProtKB/TrEMBL
      F6WHF6, H9FV18
      Related
      ENSMMUP00000014773.4, ENSMMUT00000015769.4
      Conserved Domains (3) summary
      smart00702
      Location:345 → 479
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
      pfam07719
      Location:207 → 238
      TPR_2; Tetratricopeptide repeat
      pfam08336
      Location:24 → 153
      P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
    Nucleotide Protein
    Heading Accession and Version

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