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    MMP2 matrix metallopeptidase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698478, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MMP2provided by VGNC
    Official Full Name
    matrix metallopeptidase 2provided by VGNC
    Primary source
    VGNC:VGNC:74897
    See related
    Ensembl:ENSMMUG00000004475
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MMP2 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (42608075..42635543)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (39535792..39563109)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene iroquois homeobox 6 Neighboring gene uncharacterized LOC106995029 Neighboring gene lysophosphatidylcholine acyltransferase 2 Neighboring gene uncharacterized LOC114674442 Neighboring gene calpain small subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. IGF2, IGF binding protein 1, and matrix metalloproteinases 2 and 9 in implantation-stage endometrium following immunoneutralization of vascular endothelial growth factor in the rhesus monkey. Ghosh D, et al. Reproduction, 2011 Apr. PMID 21292726
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. IGF2, IGF binding protein 1, and matrix metalloproteinases 2 and 9 in implantation-stage endometrium following immunoneutralization of vascular endothelial growth factor in the rhesus monkey.
      Title: IGF2, IGF binding protein 1, and matrix metalloproteinases 2 and 9 in implantation-stage endometrium following immunoneutralization of vascular endothelial growth factor in the rhesus monkey.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in collagen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to hypoxia IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tissue remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    72 kDa type IV collagenase
    Names
    matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
    XP_001087939.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      42608075..42635543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001087939.4 → XP_001087939.2  72 kDa type IV collagenase

      UniProtKB/TrEMBL
      A0A1D5QTJ7, G7NPB5, H9Z1R6
      Related
      ENSMMUP00000051376.2, ENSMMUT00000058575.2
      Conserved Domains (4) summary
      smart00059
      Location:342 → 390
      FN2; Fibronectin type 2 domain
      cd00094
      Location:466 → 660
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      pfam00413
      Location:118 → 446
      Peptidase_M10; Matrixin
      pfam01471
      Location:70 → 97
      PG_binding_1; Putative peptidoglycan binding domain
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials