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    SPTB spectrin beta, erythrocytic [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711142, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPTBprovided by VGNC
    Official Full Name
    spectrin beta, erythrocyticprovided by VGNC
    Primary source
    VGNC:VGNC:77870
    See related
    Ensembl:ENSMMUG00000019172
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPTB in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (126808714..126945829, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (126694855..126831738, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S10 pseudogene Neighboring gene protein phosphatase 1 regulatory subunit 36 Neighboring gene pleckstrin homology and RhoGEF domain containing G3 Neighboring gene churchill domain containing 1 Neighboring gene glutathione peroxidase 2 Neighboring gene RAB15, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cortical actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of spectrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    spectrin beta chain, erythrocytic

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      126808714..126945829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015143893.2 → XP_014999379.2  spectrin beta chain, erythrocytic isoform X2

      UniProtKB/TrEMBL
      F6SKK1
      Conserved Domains (5) summary
      smart00150
      Location:1383 → 1473
      SPEC; Spectrin repeats
      COG5069
      Location:48 → 452
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:953 → 1166
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cd10571
      Location:2179 → 2257
      PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
      pfam00435
      Location:420 → 523
      Spectrin; Spectrin repeat

    2. XM_015143891.2 → XP_014999377.2  spectrin beta chain, erythrocytic isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q6B2, A0A1D5QC83, F6SKK1
      Conserved Domains (5) summary
      smart00150
      Location:1383 → 1473
      SPEC; Spectrin repeats
      COG5069
      Location:48 → 452
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:528 → 740
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cd10571
      Location:2179 → 2284
      PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
      pfam00435
      Location:420 → 523
      Spectrin; Spectrin repeat

    3. XM_015143892.2 → XP_014999378.2  spectrin beta chain, erythrocytic isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q6B2, A0A1D5QC83, F6SKK1
      Related
      ENSMMUP00000045652.2, ENSMMUT00000061465.2
      Conserved Domains (5) summary
      smart00150
      Location:1383 → 1473
      SPEC; Spectrin repeats
      COG5069
      Location:48 → 452
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:528 → 740
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cd10571
      Location:2179 → 2284
      PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
      pfam00435
      Location:420 → 523
      Spectrin; Spectrin repeat
    Nucleotide Protein
    Heading Accession and Version

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