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    TBR1 T-box brain transcription factor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701176, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TBR1provided by VGNC
    Official Full Name
    T-box brain transcription factor 1provided by VGNC
    Primary source
    VGNC:VGNC:78111
    See related
    Ensembl:ENSMMUG00000011911
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TBR1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (48452322..48462623)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (48110247..48120031)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene TRAF family member associated NFKB activator Neighboring gene uncharacterized LOC106992595 Neighboring gene proteasome 26S subunit, non-ATPase 14 Neighboring gene solute carrier family 4 member 10 Neighboring gene small nucleolar RNA U13 Neighboring gene dipeptidyl peptidase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Maternal deprivation alters expression of neural maturation gene tbr1 in the amygdala paralaminar nucleus in infant female macaques. de Campo DM, et al. Dev Psychobiol, 2017 Mar. PMID 27917473, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Maternal deprivation downregulates expression of neural maturation gene tbr1 in the amygdala paralaminar nucleus in infant female macaques.
      Title: Maternal deprivation alters expression of neural maturation gene tbr1 in the amygdala paralaminar nucleus in infant female macaques.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell fate specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in commitment of neuronal cell to specific neuron type in forebrain IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neuron projection development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-box brain protein 1
    Names
    T-box, brain 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      48452322..48462623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110237.2 → XP_014965723.1  T-box brain protein 1

      UniProtKB/TrEMBL
      F7HMW5, H9F0Z2, I2CYF5
      Related
      ENSMMUP00000015629.4, ENSMMUT00000016686.4
      Conserved Domains (2) summary
      pfam16176
      Location:418 → 680
      T-box_assoc; T-box transcription factor-associated
      cd20204
      Location:203 → 393
      T-box_TBR1; DNA-binding domain of T-box brain protein 1 and related T-box proteins
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials