GSTA1 glutathione S-transferase alpha 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: GSTA1
Gene description: glutathione S-transferase alpha 1
See related: Ensembl:ENSMMUG00000017137
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
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Genomic context

Location:: chromosome: 4

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	4	NC_041757.1 (116760886..116772526)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	Unplaced Scaffold	NW_014811545.1 (3459..15091)

Chromosome 4 - NC_041757.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

G66731 (e-PCR)
- UniSTS:166944

RH71356 (e-PCR)
- UniSTS:76642

GSTA2_2506 (e-PCR)
- UniSTS:280745

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables glutathione transferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in glutathione metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in xenobiotic metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular exosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: glutathione S-transferase alpha 1

Names: glutathione S-transferase A1

NP_001182705.1

EC 2.5.1.18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001195776.1 → NP_001182705.1 glutathione S-transferase alpha 1

See identical proteins and their annotated locations for NP_001182705.1

Status: VALIDATED

Source sequence(s)

CO582862

UniProtKB/TrEMBL

A0A5F7ZAC1, G7MPL2

Related

ENSMMUP00000062543.1, ENSMMUT00000087223.1

Conserved Domains (2) summary

cd03208
Location:86 → 220

GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases

cd03077
Location:4 → 82

GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...