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    EXOSC3 exosome component 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716347, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EXOSC3provided by VGNC
    Official Full Name
    exosome component 3provided by VGNC
    Primary source
    VGNC:VGNC:72292
    See related
    Ensembl:ENSMMUG00000008665
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EXOSC3 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (46328427..46348893)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (46246813..46267319)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene multifunctional protein ADE2-like Neighboring gene DDB1 and CUL4 associated factor 10 Neighboring gene tRNA methyltransferase 10B Neighboring gene FERM and PDZ domain containing 1 Neighboring gene translocase of outer mitochondrial membrane 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in CUT catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in TRAMP-dependent tRNA surveillance pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in U4 snRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent rRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in poly(A)-dependent snoRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cytoplasmic exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of nuclear exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    exosome complex component RRP40

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257940.2 → NP_001244869.1  exosome complex component RRP40

      See identical proteins and their annotated locations for NP_001244869.1

      Status: PROVISIONAL

      Source sequence(s)
      JU322413
      UniProtKB/TrEMBL
      A0A1D5Q1B3, F7F3T0, G7NF05
      Conserved Domains (3) summary
      COG1097
      Location:26 → 274
      Rrp4; Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains [Translation, ribosomal structure and biogenesis]
      cd05790
      Location:108 → 193
      S1_Rrp40; S1_Rrp40: Rrp40 S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. Rrp4 protein is a subunit of the exosome complex. The exosome plays a central role in 3' to 5' RNA processing and degradation ...
      pfam15985
      Location:197 → 243
      KH_6; KH domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      46328427..46348893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015117404.2 → XP_014972890.1  exosome complex component RRP40 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q1B3
      Conserved Domains (1) summary
      cl09927
      Location:108 → 159
      S1_like; S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. ...

    2. XM_015117403.2 → XP_014972889.1  exosome complex component RRP40 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q1B3, F7F3T0, G7NF05
      Conserved Domains (3) summary
      COG1097
      Location:26 → 274
      Rrp4; Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains [Translation, ribosomal structure and biogenesis]
      cd05790
      Location:108 → 193
      S1_Rrp40; S1_Rrp40: Rrp40 S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. Rrp4 protein is a subunit of the exosome complex. The exosome plays a central role in 3' to 5' RNA processing and degradation ...
      pfam15985
      Location:197 → 243
      KH_6; KH domain

    3. XM_015117402.2 → XP_014972888.1  exosome complex component RRP40 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q1B3, F7F3T0, G7NF05
      Related
      ENSMMUP00000041825.2, ENSMMUT00000078285.2
      Conserved Domains (3) summary
      COG1097
      Location:26 → 274
      Rrp4; Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains [Translation, ribosomal structure and biogenesis]
      cd05790
      Location:108 → 193
      S1_Rrp40; S1_Rrp40: Rrp40 S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. Rrp4 protein is a subunit of the exosome complex. The exosome plays a central role in 3' to 5' RNA processing and degradation ...
      pfam15985
      Location:197 → 243
      KH_6; KH domain

    RNA

    1. XR_003723008.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials