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    CDT1 chromatin licensing and DNA replication factor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711530, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CDT1provided by VGNC
    Official Full Name
    chromatin licensing and DNA replication factor 1provided by VGNC
    Primary source
    VGNC:VGNC:71092
    See related
    Ensembl:ENSMMUG00000013823
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CDT1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (75823884..75829146)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (73636347..73641222)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene ERV-BabFcenv provirus ancestral Env polyprotein-like Neighboring gene uncharacterized LOC106995121 Neighboring gene adenine phosphoribosyltransferase Neighboring gene galactosamine (N-acetyl)-6-sulfatase Neighboring gene uncharacterized LOC114674394

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA polymerase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA replication preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA replication factor Cdt1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      75823884..75829146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126794.2 → XP_014982280.2  DNA replication factor Cdt1

      UniProtKB/TrEMBL
      F6T5D2, G7NQ88
      Related
      ENSMMUP00000018173.4, ENSMMUT00000019406.4
      Conserved Domains (3) summary
      cd08674
      Location:173 → 357
      Cdt1_m; The middle winged helix fold of replication licensing factor Cdt1 binds geminin to inhibit binding of the MCM complex to origins of replication and DNA
      cd08767
      Location:420 → 542
      Cdt1_c; The C-terminal fold of replication licensing factor Cdt1 is essential for Cdt1 activity and directly interacts with MCM2-7 helicase
      PHA03247
      Location:15 → 192
      PHA03247; large tegument protein UL36; Provisional
    Nucleotide Protein
    Heading Accession and Version

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