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    DCP2 decapping mRNA 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694225, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DCP2provided by VGNC
    Official Full Name
    decapping mRNA 2provided by VGNC
    Primary source
    VGNC:VGNC:71700
    Locus tag
    EGK_16754
    See related
    Ensembl:ENSMMUG00000013553
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DCP2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (110446421..110535009)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (110352472..110441441)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106998889 Neighboring gene glycine cleavage system H protein, mitochondrial Neighboring gene signal recognition particle 19 Neighboring gene receptor accessory protein 5 Neighboring gene survival motor neuron protein-like Neighboring gene MCC regulator of WNT signaling pathway Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene testis specific serine kinase 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables manganese ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    m7GpppN-mRNA hydrolase
    Names
    DCP2 decapping enzyme homolog
    mRNA-decapping enzyme 2
    NP_001253393.1
    XP_014996053.1
    XP_014996054.1
    XP_028704872.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266464.1 → NP_001253393.1  m7GpppN-mRNA hydrolase

      See identical proteins and their annotated locations for NP_001253393.1

      Status: PROVISIONAL

      Source sequence(s)
      JU471049
      UniProtKB/TrEMBL
      A0A5S6RAB2, A0A8J8YEL4, F7FRQ8, G7MVJ6
      Related
      ENSMMUP00000017826.4, ENSMMUT00000019031.4
      Conserved Domains (2) summary
      cd03672
      Location:97 → 246
      Dcp2p; mRNA decapping enzyme 2 (Dcp2p), the catalytic subunit, and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical ...
      pfam05026
      Location:12 → 93
      DCP2; Dcp2, box A domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      110446421..110535009
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015140567.2 → XP_014996053.1  m7GpppN-mRNA hydrolase isoform X1

      Conserved Domains (2) summary
      cd03672
      Location:94 → 243
      Dcp2p; mRNA decapping enzyme 2 (Dcp2p), the catalytic subunit, and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical ...
      pfam05026
      Location:15 → 90
      DCP2; Dcp2, box A domain

    2. XM_015140568.2 → XP_014996054.1  m7GpppN-mRNA hydrolase isoform X2

      UniProtKB/TrEMBL
      F7CI46
      Related
      ENSMMUP00000034230.3, ENSMMUT00000041194.3
      Conserved Domains (2) summary
      cd03672
      Location:97 → 246
      Dcp2p; mRNA decapping enzyme 2 (Dcp2p), the catalytic subunit, and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical ...
      pfam05026
      Location:12 → 93
      DCP2; Dcp2, box A domain

    3. XM_028849039.1 → XP_028704872.1  m7GpppN-mRNA hydrolase isoform X3

      Conserved Domains (1) summary
      cd03672
      Location:47 → 196
      Dcp2p; mRNA decapping enzyme 2 (Dcp2p), the catalytic subunit, and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical ...
    Nucleotide Protein
    Heading Accession and Version

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