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    NUMB NUMB endocytic adaptor protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696528, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NUMBprovided by VGNC
    Official Full Name
    NUMB endocytic adaptor proteinprovided by VGNC
    Primary source
    VGNC:VGNC:75557
    See related
    Ensembl:ENSMMUG00000020196
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NUMB in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (135402244..135596342, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (135644883..135844129, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999487 Neighboring gene papilin, proteoglycan like sulfated glycoprotein Neighboring gene uncharacterized LOC114679597 Neighboring gene HEAT repeat containing 4 Neighboring gene ribosomal oxygenase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein numb homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      135402244..135596342 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144060.2 → XP_014999546.2  protein numb homolog isoform X4

      UniProtKB/TrEMBL
      F6WLS8, H9ZER2
      Conserved Domains (3) summary
      PRK10263
      Location:329 → 511
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:246 → 324
      NumbF; NUMB domain

    2. XM_028851655.1 → XP_028707488.1  protein numb homolog isoform X7

      UniProtKB/TrEMBL
      A0A1D5QSB5, F6WLR7, F6WLS8, F7AGV6, H9ETQ5
      Related
      ENSMMUP00000032751.2, ENSMMUT00000039687.3
      Conserved Domains (3) summary
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:249 → 327
      NumbF; NUMB domain
      pfam09770
      Location:364 → 530
      PAT1; Topoisomerase II-associated protein PAT1

    3. XM_015144058.2 → XP_014999544.2  protein numb homolog isoform X3

      UniProtKB/TrEMBL
      F6WLS8, H9ZER3
      Conserved Domains (3) summary
      PRK10263
      Location:332 → 514
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:249 → 327
      NumbF; NUMB domain

    4. XM_015144062.2 → XP_014999548.2  protein numb homolog isoform X5

      UniProtKB/TrEMBL
      F6WLS8, H9ETT6
      Conserved Domains (3) summary
      PRK12323
      Location:370 → 574
      PRK12323; DNA polymerase III subunit gamma/tau
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:260 → 338
      NumbF; NUMB domain

    5. XM_015144053.2 → XP_014999539.2  protein numb homolog isoform X1

      UniProtKB/TrEMBL
      A0A8J8YMY1, F6WLS8, G7MYL6, I0FVZ8
      Related
      ENSMMUP00000043487.2, ENSMMUT00000056614.2
      Conserved Domains (3) summary
      PRK10263
      Location:343 → 525
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:260 → 338
      NumbF; NUMB domain

    6. XM_028851656.1 → XP_028707489.1  protein numb homolog isoform X8

      UniProtKB/TrEMBL
      F6WLS8, F6WLT7, H9G178
      Related
      ENSMMUP00000026590.3, ENSMMUT00000028414.4
      Conserved Domains (3) summary
      PRK12323
      Location:356 → 560
      PRK12323; DNA polymerase III subunits gamma and tau; Provisional
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:244 → 324
      NumbF; NUMB domain

    7. XM_015144059.2 → XP_014999545.2  protein numb homolog isoform X4

      UniProtKB/TrEMBL
      F6WLS8, H9ZER2
      Conserved Domains (3) summary
      PRK10263
      Location:329 → 511
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:246 → 324
      NumbF; NUMB domain

    8. XM_015144064.2 → XP_014999550.2  protein numb homolog isoform X7

      UniProtKB/TrEMBL
      A0A1D5QSB5, F6WLR7, F6WLS8, F7AGV6, H9ETQ5
      Conserved Domains (3) summary
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:249 → 327
      NumbF; NUMB domain
      pfam09770
      Location:364 → 530
      PAT1; Topoisomerase II-associated protein PAT1

    9. XM_015144056.2 → XP_014999542.2  protein numb homolog isoform X3

      UniProtKB/TrEMBL
      F6WLS8, H9ZER3
      Conserved Domains (3) summary
      PRK10263
      Location:332 → 514
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:249 → 327
      NumbF; NUMB domain

    10. XM_015144063.2 → XP_014999549.2  protein numb homolog isoform X6

      UniProtKB/TrEMBL
      F6WLS8, I0FVZ9
      Conserved Domains (3) summary
      PRK12323
      Location:367 → 571
      PRK12323; DNA polymerase III subunit gamma/tau
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:257 → 335
      NumbF; NUMB domain

    11. XM_015144054.2 → XP_014999540.2  protein numb homolog isoform X2

      UniProtKB/TrEMBL
      F6WLS8
      Conserved Domains (3) summary
      PRK10263
      Location:340 → 522
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:257 → 335
      NumbF; NUMB domain

    12. XM_015144061.2 → XP_014999547.2  protein numb homolog isoform X5

      UniProtKB/TrEMBL
      F6WLS8, H9ETT6
      Conserved Domains (3) summary
      PRK12323
      Location:370 → 574
      PRK12323; DNA polymerase III subunit gamma/tau
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:260 → 338
      NumbF; NUMB domain

    13. XM_015144051.2 → XP_014999537.2  protein numb homolog isoform X1

      UniProtKB/TrEMBL
      A0A8J8YMY1, F6WLS8, G7MYL6, I0FVZ8
      Conserved Domains (3) summary
      PRK10263
      Location:343 → 525
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:260 → 338
      NumbF; NUMB domain

    14. XM_028851654.1 → XP_028707487.1  protein numb homolog isoform X7

      UniProtKB/TrEMBL
      A0A1D5QSB5, F6WLR7, F6WLS8, F7AGV6, H9ETQ5
      Related
      ENSMMUP00000026592.3, ENSMMUT00000028416.4
      Conserved Domains (3) summary
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:249 → 327
      NumbF; NUMB domain
      pfam09770
      Location:364 → 530
      PAT1; Topoisomerase II-associated protein PAT1

    15. XM_015144052.2 → XP_014999538.2  protein numb homolog isoform X1

      UniProtKB/TrEMBL
      A0A8J8YMY1, F6WLS8, G7MYL6, I0FVZ8
      Conserved Domains (3) summary
      PRK10263
      Location:343 → 525
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:260 → 338
      NumbF; NUMB domain

    16. XM_015144057.2 → XP_014999543.2  protein numb homolog isoform X3

      UniProtKB/TrEMBL
      F6WLS8, H9ZER3
      Related
      ENSMMUP00000026591.4, ENSMMUT00000028415.4
      Conserved Domains (3) summary
      PRK10263
      Location:332 → 514
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 157
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:249 → 327
      NumbF; NUMB domain

    17. XM_028851650.1 → XP_028707483.1  protein numb homolog isoform X1

      UniProtKB/TrEMBL
      A0A8J8YMY1, F6WLS8, G7MYL6, I0FVZ8
      Conserved Domains (3) summary
      PRK10263
      Location:343 → 525
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:260 → 338
      NumbF; NUMB domain

    18. XM_028851651.1 → XP_028707484.1  protein numb homolog isoform X1

      UniProtKB/TrEMBL
      A0A8J8YMY1, F6WLS8, G7MYL6, I0FVZ8
      Conserved Domains (3) summary
      PRK10263
      Location:343 → 525
      PRK10263; DNA translocase FtsK; Provisional
      cd01268
      Location:23 → 168
      PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
      pfam06311
      Location:260 → 338
      NumbF; NUMB domain
    Nucleotide Protein
    Heading Accession and Version

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