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    KSR1 kinase suppressor of ras 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706388, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KSR1provided by VGNC
    Official Full Name
    kinase suppressor of ras 1provided by VGNC
    Primary source
    VGNC:VGNC:74221
    See related
    Ensembl:ENSMMUG00000017888
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KSR1 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (23079684..23252130)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (21447555..21620109)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114673080 Neighboring gene TBC1 domain family member 3D-like Neighboring gene myb/SANT-like DNA-binding domain-containing protein 3 pseudogene Neighboring gene galectin-9 Neighboring gene nitric oxide synthase, inducible-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kinase suppressor of Ras 1
    XP_014974364.1
    XP_014974365.1
    XP_014974366.1
    XP_014974367.1
    XP_014974369.1
    XP_028691962.1
    XP_028691963.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      23079684..23252130
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015118879.2 → XP_014974365.1  kinase suppressor of Ras 1 isoform X2

      UniProtKB/TrEMBL
      G7NGI0
      Conserved Domains (4) summary
      cd00029
      Location:348 → 390
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd14152
      Location:576 → 854
      STKc_KSR1; Catalytic domain of the Serine/Threonine Kinase, Kinase Suppressor of Ras 1
      pfam07714
      Location:577 → 841
      Pkinase_Tyr; Protein tyrosine kinase
      pfam13543
      Location:41 → 168
      KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

    2. XM_015118878.2 → XP_014974364.1  kinase suppressor of Ras 1 isoform X1

      UniProtKB/TrEMBL
      G7NGI0
      Conserved Domains (4) summary
      cd00029
      Location:348 → 390
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd14152
      Location:590 → 868
      STKc_KSR1; Catalytic domain of the Serine/Threonine Kinase, Kinase Suppressor of Ras 1
      pfam07714
      Location:591 → 855
      Pkinase_Tyr; Protein tyrosine kinase
      pfam13543
      Location:41 → 168
      KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

    3. XM_015118881.2 → XP_014974367.1  kinase suppressor of Ras 1 isoform X5

      UniProtKB/TrEMBL
      G7NGI0
      Conserved Domains (4) summary
      cd00029
      Location:348 → 390
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd14152
      Location:590 → 868
      STKc_KSR1; Catalytic domain of the Serine/Threonine Kinase, Kinase Suppressor of Ras 1
      pfam07714
      Location:591 → 855
      Pkinase_Tyr; Protein tyrosine kinase
      pfam13543
      Location:41 → 168
      KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

    4. XM_028836129.1 → XP_028691962.1  kinase suppressor of Ras 1 isoform X4

      UniProtKB/TrEMBL
      G7NGI0
      Related
      ENSMMUP00000023517.4, ENSMMUT00000025138.4
      Conserved Domains (3) summary
      cd00029
      Location:348 → 390
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd14152
      Location:590 → 868
      STKc_KSR1; Catalytic domain of the Serine/Threonine Kinase, Kinase Suppressor of Ras 1
      pfam13543
      Location:41 → 168
      KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

    5. XM_015118880.2 → XP_014974366.1  kinase suppressor of Ras 1 isoform X3

      UniProtKB/TrEMBL
      G7NGI0
      Conserved Domains (4) summary
      cd00029
      Location:348 → 390
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd14152
      Location:590 → 868
      STKc_KSR1; Catalytic domain of the Serine/Threonine Kinase, Kinase Suppressor of Ras 1
      pfam07714
      Location:591 → 855
      Pkinase_Tyr; Protein tyrosine kinase
      pfam13543
      Location:41 → 168
      KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

    6. XM_028836130.1 → XP_028691963.1  kinase suppressor of Ras 1 isoform X7

      UniProtKB/TrEMBL
      F7F1U6
      Conserved Domains (2) summary
      cd14152
      Location:453 → 731
      STKc_KSR1; Catalytic domain of the Serine/Threonine Kinase, Kinase Suppressor of Ras 1
      cd20872
      Location:209 → 255
      C1_KSR1; protein kinase C conserved region 1 (C1 domain) found in kinase suppressor of Ras 1 (KSR1) and similar proteins

    7. XM_015118883.2 → XP_014974369.1  kinase suppressor of Ras 1 isoform X6

      UniProtKB/TrEMBL
      F7F1U6
      Conserved Domains (4) summary
      cd00029
      Location:229 → 271
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd14152
      Location:471 → 749
      STKc_KSR1; Catalytic domain of the Serine/Threonine Kinase, Kinase Suppressor of Ras 1
      pfam07714
      Location:472 → 736
      Pkinase_Tyr; Protein tyrosine kinase
      pfam13543
      Location:11 → 49
      KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

    RNA

    1. XR_003723672.1 RNA Sequence

    2. XR_003723673.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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