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    DHX58 DExH-box helicase 58 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709116, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DHX58provided by VGNC
    Official Full Name
    DExH-box helicase 58provided by VGNC
    Primary source
    VGNC:VGNC:71815
    Locus tag
    EGK_08724
    See related
    Ensembl:ENSMMUG00000014755
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DHX58 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (53222476..53233857, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (47945139..47956727, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene NFKB inhibitor interacting Ras like 2 Neighboring gene zinc finger protein 385C Neighboring gene chromosome 16 C17orf113 homolog Neighboring gene lysine acetyltransferase 2A Neighboring gene heat shock protein family B (small) member 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of interferon-beta production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable ATP-dependent RNA helicase DHX58
    Names
    Putative ATP-dependent RNA helicase DHX58
    XP_001108799.2
    XP_014975171.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      53222476..53233857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015119685.2 → XP_014975171.2  probable ATP-dependent RNA helicase DHX58

      UniProtKB/TrEMBL
      A0A1D5RCV0, F7G3U0, H9Z151
      Related
      ENSMMUP00000019371.4, ENSMMUT00000020699.4
      Conserved Domains (4) summary
      cd15806
      Location:552 → 664
      LGP2_C; C-terminal domain of Laboratory of Genetics and Physiology 2 (LGP2), a cytoplasmic viral RNA receptor
      cd12090
      Location:227 → 345
      MDA5_ID; Insert domain of MDA5
      cd18802
      Location:349 → 483
      SF2_C_dicer; C-terminal helicase domain of the endoribonuclease Dicer
      cl28899
      Location:1 → 200
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

    2. XM_001108799.4 → XP_001108799.2  probable ATP-dependent RNA helicase DHX58

      UniProtKB/TrEMBL
      A0A1D5RCV0, F7G3U0, H9Z151
      Related
      ENSMMUP00000058143.2, ENSMMUT00000059845.2
      Conserved Domains (4) summary
      cd15806
      Location:552 → 664
      LGP2_C; C-terminal domain of Laboratory of Genetics and Physiology 2 (LGP2), a cytoplasmic viral RNA receptor
      cd12090
      Location:227 → 345
      MDA5_ID; Insert domain of MDA5
      cd18802
      Location:349 → 483
      SF2_C_dicer; C-terminal helicase domain of the endoribonuclease Dicer
      cl28899
      Location:1 → 200
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

    RNA

    1. XR_001440459.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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