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    TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702208, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TIE1provided by VGNC
    Official Full Name
    tyrosine kinase with immunoglobulin like and EGF like domains 1provided by VGNC
    Primary source
    VGNC:VGNC:78355
    Locus tag
    EGK_00658
    See related
    Ensembl:ENSMMUG00000010660
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TIE1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (181138608..181161635, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (42794970..42818118)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114672740 Neighboring gene ELOVL fatty acid elongase 1 Neighboring gene uncharacterized LOC106998150 Neighboring gene cell division cycle 20 Neighboring gene chromosome 1 C1orf210 homolog Neighboring gene uncharacterized LOC114672736

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase receptor Tie-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      181138608..181161635 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015137399.2 → XP_014992885.1  tyrosine-protein kinase receptor Tie-1

      UniProtKB/TrEMBL
      A0A1D5QER9, A0A663DGD0, A0A8J8XCU7, F7B4Q3, G7MGE5
      Related
      ENSMMUP00000013971.3, ENSMMUT00000014912.4
      Conserved Domains (7) summary
      smart00219
      Location:839 → 1107
      TyrKc; Tyrosine kinase, catalytic domain
      cd00054
      Location:227 → 256
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:644 → 736
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05089
      Location:836 → 1132
      PTKc_Tie1; Catalytic domain of the Protein Tyrosine Kinase, Tie1
      pfam00041
      Location:548 → 632
      fn3; Fibronectin type III domain
      pfam00047
      Location:129 → 210
      ig; Immunoglobulin domain
      pfam07974
      Location:315 → 344
      EGF_2; EGF-like domain
    Nucleotide Protein
    Heading Accession and Version

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