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    PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702987, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PPM1Aprovided by VGNC
    Official Full Name
    protein phosphatase, Mg2+/Mn2+ dependent 1Aprovided by VGNC
    Primary source
    VGNC:VGNC:84422
    See related
    Ensembl:ENSMMUG00000010464
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PPM1A in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (122343294..122395709)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (122227344..122275110)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene proteasome subunit alpha type-3 pseudogene Neighboring gene dehydrogenase/reductase 7 Neighboring gene eukaryotic translation initiation factor 2 subunit 3 pseudogene Neighboring gene chromosome 7 C14orf39 homolog Neighboring gene uncharacterized LOC114679576

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables manganese ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase 1A
    XP_001096358.2
    XP_014999302.1
    XP_014999303.1
    XP_014999304.1
    XP_014999305.1
    XP_028707423.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      122343294..122395709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001096358.4 → XP_001096358.2  protein phosphatase 1A isoform X2

      See identical proteins and their annotated locations for XP_001096358.2

      UniProtKB/TrEMBL
      A0A1D5R334, G7MY75
      Related
      ENSMMUP00000054719.2, ENSMMUT00000053304.2
      Conserved Domains (2) summary
      cd00143
      Location:96 → 364
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:358 → 433
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    2. XM_028851590.1 → XP_028707423.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A1D5QCM8, A0A5F8AQS8
      Related
      ENSMMUP00000080202.1, ENSMMUT00000081472.1
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    3. XM_015143819.2 → XP_014999305.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A1D5QCM8, A0A5F8AQS8
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    4. XM_015143816.2 → XP_014999302.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A1D5QCM8, A0A5F8AQS8
      Related
      ENSMMUP00000045797.2, ENSMMUT00000074353.2
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    5. XM_015143818.2 → XP_014999304.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A1D5QCM8, A0A5F8AQS8
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

    6. XM_015143817.2 → XP_014999303.1  protein phosphatase 1A isoform X1

      UniProtKB/TrEMBL
      A0A1D5QCM8, A0A5F8AQS8
      Related
      ENSMMUP00000013710.4, ENSMMUT00000014636.4
      Conserved Domains (2) summary
      cd00143
      Location:23 → 291
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      pfam07830
      Location:285 → 363
      PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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