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    TNKS tankyrase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699004, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TNKSprovided by VGNC
    Official Full Name
    tankyraseprovided by VGNC
    Primary source
    VGNC:VGNC:78601
    Locus tag
    EGK_18700
    See related
    Ensembl:ENSMMUG00000000965
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TNKS in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (10786991..11011350, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (10029702..10297465, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-124a-2 Neighboring gene small nucleolar RNA U13 Neighboring gene microRNA mir-597 Neighboring gene uncharacterized LOC114680179 Neighboring gene uncharacterized LOC114680180 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD+-protein poly-ADP-ribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    poly [ADP-ribose] polymerase tankyrase-1
    Names
    Tankyrase-1
    NP_001248210.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261281.1 → NP_001248210.1  poly [ADP-ribose] polymerase tankyrase-1

      See identical proteins and their annotated locations for NP_001248210.1

      Status: PROVISIONAL

      Source sequence(s)
      JU320126
      UniProtKB/TrEMBL
      A0A1D5RCD4, A0A8J8XKK4, F6QQJ9, G7N0J0
      Related
      ENSMMUP00000001295.2, ENSMMUT00000001377.4
      Conserved Domains (6) summary
      PTZ00322
      Location:177 → 269
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PHA02876
      Location:231 → 616
      PHA02876; ankyrin repeat protein; Provisional
      cd09524
      Location:1024 → 1089
      SAM_tankyrase1,2; SAM domain of tankyrase1,2 subfamily
      PHA03095
      Location:652 → 976
      PHA03095; ankyrin-like protein; Provisional
      cd01438
      Location:1091 → 1313
      tankyrase_like; Tankyrases interact with the telomere reverse transcriptase complex (TERT). Tankyrase 1 poly-ADP-ribosylates Telomere Repeat Binding Factor 1 (TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or TRF1. The tankyrases also contain multiple ankyrin ...
      sd00045
      Location:371 → 399
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      10786991..11011350 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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