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    CSTF2 cleavage stimulation factor subunit 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701235, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CSTF2provided by VGNC
    Official Full Name
    cleavage stimulation factor subunit 2provided by VGNC
    Primary source
    VGNC:VGNC:71536
    Locus tag
    EGK_20728
    See related
    Ensembl:ENSMMUG00000013008
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CSTF2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (97626291..97647248)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (95006322..95028433)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene thymosin beta-4 pseudogene Neighboring gene double-strand-break repair protein rad21 homolog pseudogene Neighboring gene small nucleolar RNA SNORA9 Neighboring gene NADPH oxidase 1 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mRNA cleavage and polyadenylation specificity factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cleavage stimulation factor subunit 2
    Names
    cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      97626291..97647248
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127803.2 → XP_014983289.1  cleavage stimulation factor subunit 2 isoform X5

      UniProtKB/TrEMBL
      A0A1D5QUW9, H9F9L6
      Related
      ENSMMUP00000051849.2, ENSMMUT00000054002.2
      Conserved Domains (5) summary
      TIGR01628
      Location:5 → 318
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      PRK07764
      Location:241 → 436
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd12671
      Location:18 → 92
      RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
      pfam14304
      Location:533 → 573
      CSTF_C; Transcription termination and cleavage factor C-terminal
      pfam14327
      Location:112 → 191
      CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2

    2. XM_028841850.1 → XP_028697683.1  cleavage stimulation factor subunit 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QYY1, H9F9L6
      Related
      ENSMMUP00000053263.2, ENSMMUT00000073042.2
      Conserved Domains (5) summary
      PRK14718
      Location:441 → 498
      PRK14718; ribonuclease III; Provisional
      PRK07764
      Location:247 → 485
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd12671
      Location:18 → 92
      RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
      pfam14304
      Location:582 → 622
      CSTF_C; Transcription termination and cleavage factor C-terminal
      pfam14327
      Location:112 → 191
      CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2

    3. XM_001089558.4 → XP_001089558.2  cleavage stimulation factor subunit 2 isoform X3

      See identical proteins and their annotated locations for XP_001089558.2

      UniProtKB/TrEMBL
      A0A1D5R4X5, A0A5S6RDF4, A0A8J8YSW5, G7NSF8, H9F9L6
      Related
      ENSMMUP00000055362.2, ENSMMUT00000073319.2
      Conserved Domains (5) summary
      cd12671
      Location:18 → 92
      RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
      pfam14304
      Location:553 → 593
      CSTF_C; Transcription termination and cleavage factor C-terminal
      pfam14327
      Location:113 → 191
      CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2
      cl25887
      Location:4 → 352
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cl25983
      Location:412 → 469
      Rnc; dsRNA-specific ribonuclease [Transcription]

    4. XM_015127802.2 → XP_014983288.1  cleavage stimulation factor subunit 2 isoform X4

      UniProtKB/TrEMBL
      F7HR34, H9F9L6
      Related
      ENSMMUP00000017078.4, ENSMMUT00000018243.4
      Conserved Domains (5) summary
      TIGR01628
      Location:7 → 319
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      PRK07764
      Location:234 → 443
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      pfam14304
      Location:540 → 580
      CSTF_C; Transcription termination and cleavage factor C-terminal
      pfam14327
      Location:99 → 178
      CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2
      cl17169
      Location:7 → 81
      RRM_SF; RNA recognition motif (RRM) superfamily

    5. XM_028841851.1 → XP_028697684.1  cleavage stimulation factor subunit 2 isoform X2

      UniProtKB/TrEMBL
      H9F9L6
      Conserved Domains (5) summary
      PRK14718
      Location:428 → 485
      PRK14718; ribonuclease III; Provisional
      PRK07764
      Location:234 → 472
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd12671
      Location:7 → 79
      RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
      pfam14304
      Location:569 → 609
      CSTF_C; Transcription termination and cleavage factor C-terminal
      pfam14327
      Location:99 → 178
      CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2
    Nucleotide Protein
    Heading Accession and Version

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