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    KEAP1 kelch like ECH associated protein 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720514, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KEAP1provided by VGNC
    Official Full Name
    kelch like ECH associated protein 1provided by VGNC
    Primary source
    VGNC:VGNC:73891
    Locus tag
    EGK_10100
    See related
    Ensembl:ENSMMUG00000005218
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KEAP1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (10244340..10257891, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (10520172..10537135, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene cell division cycle 37, HSP90 cochaperone Neighboring gene phosphodiesterase 4A Neighboring gene sphingosine-1-phosphate receptor 5 Neighboring gene U7 small nuclear RNA Neighboring gene autophagy related 4D cysteine peptidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic sequestering of transcription factor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kelch-like ECH-associated protein 1
    Names
    Cytosolic inhibitor of Nrf2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      10244340..10257891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015122858.2 → XP_014978344.1  kelch-like ECH-associated protein 1

      UniProtKB/TrEMBL
      A0A5F8ARU7, A0A8J8YT76, F7C3R9, G7NL03
      Conserved Domains (4) summary
      PHA03098
      Location:95 → 596
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:460 → 503
      Kelch; KELCH repeat [structural motif]
      cd18248
      Location:56 → 180
      BTB_POZ_KLHL19_KEAP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like ECH-associated protein 1 (KEAP1)
      cd18458
      Location:178 → 268
      BACK_KLHL19_KEAP1; BACK (BTB and C-terminal Kelch) domain found in Kelch-like ECH-associated protein 1 (KEAP1)

    2. XM_015122860.2 → XP_014978346.1  kelch-like ECH-associated protein 1

      UniProtKB/TrEMBL
      A0A5F8ARU7, A0A8J8YT76, F7C3R9, G7NL03
      Related
      ENSMMUP00000006905.3, ENSMMUT00000007347.4
      Conserved Domains (4) summary
      PHA03098
      Location:95 → 596
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:460 → 503
      Kelch; KELCH repeat [structural motif]
      cd18248
      Location:56 → 180
      BTB_POZ_KLHL19_KEAP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like ECH-associated protein 1 (KEAP1)
      cd18458
      Location:178 → 268
      BACK_KLHL19_KEAP1; BACK (BTB and C-terminal Kelch) domain found in Kelch-like ECH-associated protein 1 (KEAP1)

    3. XM_028839947.1 → XP_028695780.1  kelch-like ECH-associated protein 1

      UniProtKB/TrEMBL
      A0A5F8ARU7, A0A8J8YT76, F7C3R9, G7NL03
      Related
      ENSMMUP00000079797.1, ENSMMUT00000090452.1
      Conserved Domains (4) summary
      PHA03098
      Location:95 → 596
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:460 → 503
      Kelch; KELCH repeat [structural motif]
      cd18248
      Location:56 → 180
      BTB_POZ_KLHL19_KEAP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like ECH-associated protein 1 (KEAP1)
      cd18458
      Location:178 → 268
      BACK_KLHL19_KEAP1; BACK (BTB and C-terminal Kelch) domain found in Kelch-like ECH-associated protein 1 (KEAP1)

    4. XM_015122861.2 → XP_014978347.1  kelch-like ECH-associated protein 1

      UniProtKB/TrEMBL
      A0A5F8ARU7, A0A8J8YT76, F7C3R9, G7NL03
      Conserved Domains (4) summary
      PHA03098
      Location:95 → 596
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:460 → 503
      Kelch; KELCH repeat [structural motif]
      cd18248
      Location:56 → 180
      BTB_POZ_KLHL19_KEAP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like ECH-associated protein 1 (KEAP1)
      cd18458
      Location:178 → 268
      BACK_KLHL19_KEAP1; BACK (BTB and C-terminal Kelch) domain found in Kelch-like ECH-associated protein 1 (KEAP1)
    Nucleotide Protein
    Heading Accession and Version

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