CDK6 cyclin dependent kinase 6 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: CDK6provided by VGNC
Official Full Name: cyclin dependent kinase 6provided by VGNC
Primary source: VGNC:VGNC:70983
Locus tag: EGK_13940
See related: Ensembl:ENSMMUG00000008698
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	3	NC_041756.1 (113285491..113523622)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	3	NC_027895.1 (117916931..118145706, complement)

Chromosome 3 - NC_041756.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

G36999 (e-PCR)
- UniSTS:4611

G36996 (e-PCR)
- UniSTS:41995

STS-X66365 (e-PCR)
- UniSTS:50210

G36998 (e-PCR)
- UniSTS:30774

RH104316 (e-PCR)
- UniSTS:98641

G37001 (e-PCR)
- UniSTS:39260

G37000 (e-PCR)
- UniSTS:5475

RH104334 (e-PCR)
- UniSTS:98659

G42163 (e-PCR)
- UniSTS:93292

SHGC-33519 (e-PCR)
- UniSTS:5006

SHGC-35227 (e-PCR)
- UniSTS:49054

CDK6_2114 (e-PCR)
- UniSTS:280493

RH17944 (e-PCR)
- UniSTS:11220

RH66680 (e-PCR)
- UniSTS:7896

RH79066 (e-PCR)
- UniSTS:29413

HSC197 (e-PCR)
- UniSTS:255215

CDK6 (e-PCR)
- UniSTS:34801

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cyclin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cyclin-dependent protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G1/S transition of mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell dedifferentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of G2/M transition of mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of gene expression	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cyclin-dependent protein kinase holoenzyme complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cyclin-dependent kinase 6

NP_001248236.1

EC 2.7.11.22

XP_014989716.1

EC 2.7.11.22

XP_014989717.1

EC 2.7.11.22

XP_028700699.1

EC 2.7.11.22

XP_028700700.1

EC 2.7.11.22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261307.1 → NP_001248236.1 cyclin-dependent kinase 6

See identical proteins and their annotated locations for NP_001248236.1

Status: PROVISIONAL

Source sequence(s)

JU471048

UniProtKB/TrEMBL

A0A8J8YT09, F7E5V8, G7MLW4, H9EMN3

Related

ENSMMUP00000072059.1, ENSMMUT00000081151.1

Conserved Domains (1) summary

cd07862
Location:11 → 300

STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041756.1 Reference Mmul_10 Primary Assembly

Range

113285491..113523622

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015134231.2 → XP_014989717.1 cyclin-dependent kinase 6 isoform X1

UniProtKB/TrEMBL

A0A8J8YT09, F7E5V8, G7MLW4, H9EMN3

Conserved Domains (1) summary

cd07862
Location:11 → 300

STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6
XM_028844867.1 → XP_028700700.1 cyclin-dependent kinase 6 isoform X2

Conserved Domains (1) summary

cl21453
Location:11 → 233

PKc_like; Protein Kinases, catalytic domain
XM_028844866.1 → XP_028700699.1 cyclin-dependent kinase 6 isoform X1

UniProtKB/TrEMBL

A0A8J8YT09, F7E5V8, G7MLW4, H9EMN3

Conserved Domains (1) summary

cd07862
Location:11 → 300

STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6
XM_015134230.2 → XP_014989716.1 cyclin-dependent kinase 6 isoform X1

UniProtKB/TrEMBL

A0A8J8YT09, F7E5V8, G7MLW4, H9EMN3

Conserved Domains (1) summary

cd07862
Location:11 → 300

STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6