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    UCP2 uncoupling protein 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574198, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UCP2provided by VGNC
    Official Full Name
    uncoupling protein 2provided by VGNC
    Primary source
    VGNC:VGNC:78709
    See related
    Ensembl:ENSMMUG00000002605
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See UCP2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (67029922..67038811, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (66048101..66056985, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene proteasomal ATPase associated factor 1 Neighboring gene actin-related protein 2/3 complex subunit 3 Neighboring gene DnaJ heat shock protein family (Hsp40) member B13 Neighboring gene developmental pluripotency-associated protein 4 pseudogene Neighboring gene uncoupling protein 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidative phosphorylation uncoupler activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adaptive thermogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitochondrial transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitochondrial transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to cold IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dicarboxylate carrier SLC25A8; mitochondrial uncoupling protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195393.1 → NP_001182322.1  dicarboxylate carrier SLC25A8

      Status: VALIDATED

      Source sequence(s)
      AF202130, CB552023, QNVO02000111
      UniProtKB/TrEMBL
      G7NEA9
      Conserved Domains (2) summary
      PTZ00169
      Location:17 → 299
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:112 → 206
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      67029922..67038811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115112.2 → XP_014970598.1  mitochondrial uncoupling protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QS11, F7H9F2, G7NEA9
      Related
      ENSMMUP00000051553.1, ENSMMUT00000076741.2
      Conserved Domains (2) summary
      PTZ00169
      Location:17 → 299
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:112 → 206
      Mito_carr; Mitochondrial carrier protein

    2. XM_015115113.2 → XP_014970599.1  mitochondrial uncoupling protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QS11, F7H9F2, G7NEA9
      Related
      ENSMMUP00000003500.4, ENSMMUT00000003706.4
      Conserved Domains (2) summary
      PTZ00169
      Location:17 → 299
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:112 → 206
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version

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