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    ARHGAP42 Rho GTPase activating protein 42 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703141, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGAP42provided by VGNC
    Official Full Name
    Rho GTPase activating protein 42provided by VGNC
    Primary source
    VGNC:VGNC:99546
    Locus tag
    EGK_06816
    See related
    Ensembl:ENSMMUG00000022603
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP42 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (93984944..94294482)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (93605822..93917753)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene contactin 5 Neighboring gene uncharacterized LOC114672383 Neighboring gene replication protein A 32 kDa subunit pseudogene Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC114672384 Neighboring gene progesterone receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 42

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      93984944..94294482
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002799784.3 → XP_002799830.1  rho GTPase-activating protein 42

      See identical proteins and their annotated locations for XP_002799830.1

      UniProtKB/TrEMBL
      A0A1D5QEF8, A0A663DIQ7, A0A8J8XPB1, G7NBQ3
      Related
      ENSMMUP00000046427.2, ENSMMUT00000060090.2
      Conserved Domains (5) summary
      cd07634
      Location:19 → 225
      BAR_GAP10-like; The Bin/Amphiphysin/Rvs (BAR) domain of Rho GTPase activating protein 10-like
      cd12066
      Location:820 → 874
      SH3_GRAF3; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 3
      cd04374
      Location:369 → 567
      RhoGAP_Graf; RhoGAP_Graf: GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences ...
      cd01249
      Location:267 → 376
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      pfam00169
      Location:267 → 369
      PH; PH domain
    Nucleotide Protein
    Heading Accession and Version

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