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    PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703458, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PPIP5K2provided by VGNC
    Official Full Name
    diphosphoinositol pentakisphosphate kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:76128
    See related
    Ensembl:ENSMMUG00000007787
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PPIP5K2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (100507419..100585154)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (100446033..100523569)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene peptidylglycine alpha-amidating monooxygenase Neighboring gene eukaryotic translation initiation factor 3 subunit K pseudogene Neighboring gene gypsy retrotransposon integrase 1 Neighboring gene uncharacterized LOC114678870 Neighboring gene macrophage immunometabolism regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5-diphosphoinositol pentakisphosphate 1-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables diphosphoinositol pentakisphosphate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables inositol hexakisphosphate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in inositol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2
    XP_001098530.1
    XP_014995993.1
    XP_014995995.1
    XP_014995996.1
    XP_014995997.1
    XP_014995998.1
    XP_014996000.1
    XP_014996001.1
    XP_014996002.1
    XP_014996003.1
    XP_014996004.1
    XP_014996007.1
    XP_014996008.1
    XP_014996009.1
    XP_014996010.2
    XP_028705449.1
    XP_028705450.1
    XP_028705451.1
    XP_028705453.1
    XP_028705454.1
    XP_028705455.1
    XP_028705456.1
    XP_028705457.1
    XP_028705458.1
    XP_028705459.1
    XP_028705460.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      100507419..100585154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849626.1 → XP_028705459.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X22

      UniProtKB/TrEMBL
      A0A5F7ZI04
      Conserved Domains (2) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    2. XM_015140524.2 → XP_014996010.2  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X24

      UniProtKB/TrEMBL
      F7CCT0
      Conserved Domains (2) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    3. XM_028849624.1 → XP_028705457.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X19

      UniProtKB/TrEMBL
      A0A5F7ZI04
      Related
      ENSMMUP00000064247.1, ENSMMUT00000102952.1
      Conserved Domains (2) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    4. XM_015140509.2 → XP_014995995.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X2

      UniProtKB/TrEMBL
      H9FRW3
      Conserved Domains (3) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 908
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain

    5. XM_028849616.1 → XP_028705449.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZHV5, H9FRW3
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    6. XM_015140507.2 → XP_014995993.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZHV5, H9FRW3
      Related
      ENSMMUP00000064202.1, ENSMMUT00000102808.1
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    7. XM_015140514.2 → XP_014996000.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X7

      UniProtKB/TrEMBL
      H9FRW3
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    8. XM_015140516.2 → XP_014996002.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X10

      UniProtKB/TrEMBL
      A0A5F8AR65
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    9. XM_015140510.2 → XP_014995996.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X3

      UniProtKB/TrEMBL
      H9FRW3
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 894
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    10. XM_015140511.2 → XP_014995997.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5Q532, H9FRW3
      Related
      ENSMMUP00000043147.2, ENSMMUT00000057339.2
      Conserved Domains (2) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    11. XM_015140518.2 → XP_014996004.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X13

      UniProtKB/TrEMBL
      A0A5F8AR12, A0A5F8AR65
      Related
      ENSMMUP00000079828.1, ENSMMUT00000092844.1
      Conserved Domains (2) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    12. XM_015140515.2 → XP_014996001.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X9

      UniProtKB/TrEMBL
      F7CCT0
      Conserved Domains (3) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain

    13. XM_015140521.2 → XP_014996007.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X18

      UniProtKB/TrEMBL
      F7CCT0
      Conserved Domains (2) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    14. XM_015140517.2 → XP_014996003.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X11

      UniProtKB/TrEMBL
      F7CCT0
      Conserved Domains (3) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 894
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain

    15. XM_028849618.1 → XP_028705451.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X12

      UniProtKB/TrEMBL
      A0A5F7ZNE9, F7CCT0
      Related
      ENSMMUP00000067169.1, ENSMMUT00000086938.1
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 909
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    16. XM_015140512.2 → XP_014995998.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X5

      UniProtKB/TrEMBL
      F7CQD3, H9FRW3
      Related
      ENSMMUP00000010237.3, ENSMMUT00000010912.4
      Conserved Domains (2) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 894
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    17. XM_001098530.4 → XP_001098530.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X8

      See identical proteins and their annotated locations for XP_001098530.1

      UniProtKB/TrEMBL
      F7CQE1, H9FRW3
      Related
      ENSMMUP00000010236.3, ENSMMUT00000010911.4

    18. XM_028849621.1 → XP_028705454.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X15

      UniProtKB/TrEMBL
      A0A5F8AR65
      Related
      ENSMMUP00000079557.1, ENSMMUT00000110100.1
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 894
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    19. XM_028849620.1 → XP_028705453.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X14

      UniProtKB/TrEMBL
      F7CCT0
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 894
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    20. XM_028849623.1 → XP_028705456.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X17

      UniProtKB/TrEMBL
      F7CCT0
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 894
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    21. XM_015140522.2 → XP_014996008.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X20

      UniProtKB/TrEMBL
      F7CCT0
      Related
      ENSMMUP00000034246.3, ENSMMUT00000041211.3
      Conserved Domains (2) summary
      COG0189
      Location:48 → 337
      RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
      pfam00328
      Location:379 → 894
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    22. XM_028849617.1 → XP_028705450.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X6

      UniProtKB/TrEMBL
      H9FRW3
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 893
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    23. XM_028849622.1 → XP_028705455.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X16

      UniProtKB/TrEMBL
      A0A5F8AR65
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 893
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    24. XM_028849625.1 → XP_028705458.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X21

      UniProtKB/TrEMBL
      F7CCT0
      Conserved Domains (3) summary
      pfam00328
      Location:379 → 893
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:44 → 133
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:48 → 337
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    25. XM_015140523.2 → XP_014996009.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X23

      UniProtKB/TrEMBL
      H9FRW3
      Conserved Domains (1) summary
      pfam00328
      Location:140 → 670
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    26. XM_028849627.1 → XP_028705460.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X23

      UniProtKB/TrEMBL
      H9FRW3
      Conserved Domains (1) summary
      pfam00328
      Location:140 → 670
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    Nucleotide Protein
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