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    PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693918, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PIK3C3provided by VGNC
    Official Full Name
    phosphatidylinositol 3-kinase catalytic subunit type 3provided by VGNC
    Primary source
    VGNC:VGNC:75994
    See related
    Ensembl:ENSMMUG00000014553
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PIK3C3 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (40413629..40548626, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (30732010..31255949)

    Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene Ras like without CAAX 2 Neighboring gene uncharacterized LOC106994481 Neighboring gene uncharacterized LOC114673698 Neighboring gene UPF0235 protein C15orf40-like Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagy of peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in phagophore assembly site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 3-kinase catalytic subunit type 3
    Names
    phosphoinositide-3-kinase, class 3
    XP_001082892.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041771.1 Reference Mmul_10 Primary Assembly

      Range
      40413629..40548626 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001082892.4 → XP_001082892.3  phosphatidylinositol 3-kinase catalytic subunit type 3

      UniProtKB/TrEMBL
      F7GT63, G7NKM7, H9ENP3
      Related
      ENSMMUP00000019111.4, ENSMMUT00000020418.4
      Conserved Domains (3) summary
      cd08397
      Location:26 → 186
      C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
      cd00870
      Location:283 → 503
      PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
      cd00896
      Location:539 → 883
      PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase
    Nucleotide Protein
    Heading Accession and Version

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