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    LATS2 large tumor suppressor kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699957, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LATS2provided by VGNC
    Official Full Name
    large tumor suppressor kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:74239
    See related
    Ensembl:ENSMMUG00000019006
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LATS2 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (150905..247788)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (1406115..1487585, complement)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD27 Neighboring gene Sin3A associated protein 18 Neighboring gene U4 spliceosomal RNA Neighboring gene small nucleolar RNA U13 Neighboring gene 60S ribosomal protein L23a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hippo signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of organ growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase LATS2
    Names
    LATS, large tumor suppressor, homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      150905..247788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028837636.1 → XP_028693469.1  serine/threonine-protein kinase LATS2

      UniProtKB/TrEMBL
      H9H421
      Related
      ENSMMUP00000024992.3, ENSMMUT00000026709.4
      Conserved Domains (2) summary
      cd05626
      Location:664 → 1044
      STKc_LATS2; Catalytic domain of the Protein Serine/Threonine Kinase, Large Tumor Suppressor 2
      cd14398
      Location:101 → 141
      UBA_LATS2; UBA domain found in vertebrate serine/threonine-protein kinase LATS2

    2. XM_015120711.2 → XP_014976197.1  serine/threonine-protein kinase LATS2

      UniProtKB/TrEMBL
      H9H421
      Conserved Domains (2) summary
      cd05626
      Location:664 → 1044
      STKc_LATS2; Catalytic domain of the Protein Serine/Threonine Kinase, Large Tumor Suppressor 2
      cd14398
      Location:101 → 141
      UBA_LATS2; UBA domain found in vertebrate serine/threonine-protein kinase LATS2
    Nucleotide Protein
    Heading Accession and Version

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