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    GAD1 glutamate decarboxylase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 613030, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GAD1provided by VGNC
    Official Full Name
    glutamate decarboxylase 1provided by VGNC
    Primary source
    VGNC:VGNC:72862
    Locus tag
    EGK_04525
    See related
    Ensembl:ENSMMUG00000015198
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    GAD67
    Orthologs
    human mouse all
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    Genomic context

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    See GAD1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (57960027..58006388)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (57856065..57902253)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671350 Neighboring gene glutamate rich 2 Neighboring gene uncharacterized LOC114671352 Neighboring gene golgi reassembly stacking protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of glutamic acid decarboxylase in the prepubertal inhibition of the luteinizing hormone releasing hormone release in female rhesus monkeys. Mitsushima D, et al. J Neurosci, 1996 Apr 15. PMID 8786432, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutamate decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gamma-aminobutyric acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic active zone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate decarboxylase 1
    Names
    67kDa glutamate decarboxylase 1
    glutamate decarboxylase 1 (brain, 67kDa)
    glutamic acid decarboxylase
    XP_014965837.1
    XP_028686664.1
    XP_028686665.1
    XP_028686666.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      57960027..58006388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110351.2 → XP_014965837.1  glutamate decarboxylase 1 isoform X1

      UniProtKB/TrEMBL
      A0A663D8I6, A0A8J8YFI2, F6W3Q6, F6W3S5, F7GMA1, G7N8A4
      Related
      ENSMMUP00000019935.3, ENSMMUT00000021316.4
      Conserved Domains (1) summary
      pfam00282
      Location:144 → 518
      Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

    2. XM_028830832.1 → XP_028686665.1  glutamate decarboxylase 1 isoform X2

      Conserved Domains (1) summary
      cl18945
      Location:144 → 213
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    3. XM_028830833.1 → XP_028686666.1  glutamate decarboxylase 1 isoform X2

      Conserved Domains (1) summary
      cl18945
      Location:144 → 213
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    4. XM_028830831.1 → XP_028686664.1  glutamate decarboxylase 1 isoform X1

      UniProtKB/TrEMBL
      A0A663D8I6, A0A8J8YFI2, F6W3Q6, F6W3S5, F7GMA1, G7N8A4
      Related
      ENSMMUP00000019936.4, ENSMMUT00000021317.4
      Conserved Domains (1) summary
      pfam00282
      Location:144 → 518
      Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain
    Nucleotide Protein
    Heading Accession and Version

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