These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001260797.1 → NP_001247726.1  NEDD4-like E3 ubiquitin-protein ligase WWP1

   See identical proteins and their annotated locations for NP_001247726.1

   Status: PROVISIONAL

   Source sequence(s)

   JV043810

   UniProtKB/TrEMBL

   F7HIU5, H9EUR4

   Related

   ENSMMUP00000062623.1, ENSMMUT00000090686.1

   Conserved Domains (3) summary

   cd04021
   Location:17 → 140

   C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase

   COG5021
   Location:307 → 922

   HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]

   cl41773
   Location:236 → 344

   SP1-4_N; N-terminal domain of transcription factor Specificity Proteins (SP) 1-4

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference Mmul_10 Primary Assembly

Genomic

1. NC_041761.1 Reference Mmul_10 Primary Assembly

   Range

   86766579..86907763

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_015145628.2 → XP_015001114.1  NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2

   UniProtKB/TrEMBL

   H9EUR4

   Conserved Domains (3) summary

   cd04021
   Location:17 → 140

   C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase

   COG5021
   Location:307 → 889

   HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]

   cl41773
   Location:236 → 344

   SP1-4_N; N-terminal domain of transcription factor Specificity Proteins (SP) 1-4

2. XM_015145627.2 → XP_015001113.1  NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1

   UniProtKB/TrEMBL

   H9EUR4

   Conserved Domains (3) summary

   cd04021
   Location:17 → 140

   C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase

   COG5021
   Location:306 → 921

   HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]

   cl41773
   Location:235 → 343

   SP1-4_N; N-terminal domain of transcription factor Specificity Proteins (SP) 1-4

3. XM_015145629.2 → XP_015001115.1  NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X3

   Conserved Domains (4) summary

   smart00119
   Location:353 → 681

   HECTc; Domain Homologous to E6-AP Carboxyl Terminus with

   cd00078
   Location:330 → 682

   HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

   cd00201
   Location:261 → 290

   WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...

   pfam00397
   Location:113 → 142

   WW; WW domain