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    CG7458 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40441, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG7458provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037144
    Locus tag
    Dmel_CG7458
    See related
    AllianceGenome:FB:FBgn0037144
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7458; Slc22a15
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is expressed in several structures, including adult head; amnioserosa; embryonic/larval fat body; gut section; and larval somatic muscle cell. Orthologous to human SLC22A1 (solute carrier family 22 member 1) and SLC22A3 (solute carrier family 22 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7458 in Genome Data Viewer
    Location:
    79A4-79A4; 3-47 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21955110..21958041)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21948210..21951141)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45803 Neighboring gene pseudo Neighboring gene pseudo Neighboring gene long non-coding RNA:CR45757

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression. Panda D, et al. mBio, 2015 Apr 7. PMID 25852164, Free PMC Article
    2. Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Engelhart DC, et al. Int J Mol Sci, 2020 Mar 15. PMID 32183456, Free PMC Article
    3. Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. Gonsalves SE, et al. BMC Genomics, 2011 Sep 29. PMID 21958154, Free PMC Article
    4. A direct role for cohesin in gene regulation and ecdysone response in Drosophila salivary glands. Pauli A, et al. Curr Biol, 2010 Oct 26. PMID 20933422, Free PMC Article
    5. The Drosophila blood-brain barrier: development and function of a glial endothelium. Limmer S, et al. Front Neurosci, 2014. PMID 25452710, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7458-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      21955110..21958041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141117.2 → NP_649374.1  uncharacterized protein Dmel_CG7458 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649374.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNW8
      Related
      FBpp0078128
      Conserved Domains (2) summary
      cd06174
      Location:161 → 544
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:46 → 554
      2A0119; cation transport protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SX19 Q8SX19
    Q9VNW8 Q9VNW8

    Gene LinkOut

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