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    osy oskyddad [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43186, updated on 17-Dec-2024

    Summary

    Official Symbol
    osyprovided by FlyBase
    Official Full Name
    oskyddadprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053970
    Locus tag
    Dmel_CG33970
    See related
    AllianceGenome:FB:FBgn0053970
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14559; CG31085; CG33970; CG6162; CG6166; DmCG33970; Dmel\CG33970; Osy
    Summary
    Predicted to enable ABC-type transporter activity; ATP binding activity; and ATP hydrolysis activity. Located in apical plasma membrane. Is expressed in several structures, including adult fat body; adult head; embryonic dorsal epidermis; embryonic head epidermis; and embryonic ventral epidermis. Used to study autosomal recessive congenital ichthyosis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See osy in Genome Data Viewer
    Location:
    97A8-97A10; 3-90 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26318355..26362588)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22144077..22188310)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44321 Neighboring gene Aldolase 1 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR42765 Neighboring gene Nilkantha Neighboring gene pickpocket 15 Neighboring gene Aldolase 2

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity  
    enables ATP binding  
    enables ATP hydrolysis activity  
    Component Evidence Code Pubs
    located_in apical plasma membrane PubMed 
    located_in membrane  
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    oskyddad
    Names
    CG33970-PA
    CG33970-PB
    CG33970-PC
    osy-PA
    osy-PB
    osy-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      26318355..26362588
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300613.1 → NP_001287542.1  oskyddad, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287542.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86P18
      Conserved Domains (4) summary
      COG1131
      Location:54 → 321
      CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
      pfam01061
      Location:581 → 738
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:394 → 770
      ABC2_membrane_3; ABC-2 family transporter protein
      cl21455
      Location:48 → 270
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    2. NM_001038982.2 → NP_001034071.1  oskyddad, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001034071.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86P18
      Conserved Domains (4) summary
      COG1131
      Location:54 → 321
      CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
      pfam01061
      Location:581 → 738
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:394 → 770
      ABC2_membrane_3; ABC-2 family transporter protein
      cl21455
      Location:48 → 270
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    3. NM_001038981.2 → NP_001034070.1  oskyddad, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001034070.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBF7
      Conserved Domains (2) summary
      pfam01061
      Location:322 → 479
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:135 → 511
      ABC2_membrane_3; ABC-2 family transporter protein
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