nAChRbeta3 nicotinic Acetylcholine Receptor beta3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: nAChRbeta3provided by FlyBase
Official Full Name: nicotinic Acetylcholine Receptor beta3provided by FlyBase
Primary source: FLYBASE:FBgn0031261
Locus tag: Dmel_CG11822
See related: AllianceGenome:FB:FBgn0031261
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG11822; CT33131; Dbeta3; Dmel\CG11822; nAChR; nAChR-beta21C; nAChRbeta2; nAcR-21Beta; nAcRbeta-21C
Summary: Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in cholinergic synaptic transmission; monoatomic ion transmembrane transport; and regulation of membrane potential. Predicted to be located in postsynaptic membrane. Predicted to be part of acetylcholine-gated channel complex. Predicted to be active in neuron projection; plasma membrane; and synapse. Is expressed in several structures, including adult head; embryonic foregut sensory structure; embryonic head sensory system; embryonic optic lobe primordium; and sensory nervous system primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (545129..547096)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (545129..547096)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables acetylcholine-gated monoatomic cation-selective channel activity	IEA Inferred from Electronic Annotation more info
enables transmembrane signaling receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chemical synaptic transmission	IBA Inferred from Biological aspect of Ancestor more info
involved_in monoatomic ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in regulation of membrane potential	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic transmission, cholinergic	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of acetylcholine-gated channel complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in postsynaptic membrane	IEA Inferred from Electronic Annotation more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info

Names: CG11822-PA; Dbeta3; nAChRbeta3-PA; nicotinic acetylcholine receptor beta 21C

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The following sections contain reference sequences that belong to a specific genome build. Explain