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    Btbd10 BTB domain containing 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308890, updated on 27-Dec-2024

    Summary

    Official Symbol
    Btbd10provided by RGD
    Official Full Name
    BTB domain containing 10provided by RGD
    Primary source
    RGD:1306301
    See related
    EnsemblRapid:ENSRNOG00000014341 AllianceGenome:RGD:1306301
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306301
    Summary
    Predicted to be involved in phosphatidylinositol 3-kinase/protein kinase B signal transduction and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human BTBD10 (BTB domain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 79.4), Brain (RPKM 67.0) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Btbd10 in Genome Data Viewer
    Location:
    1q33
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (176865817..176923663, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (167431311..167489320, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (178138562..178196551, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099909 Neighboring gene basic helix-loop-helix ARNT like 1 Neighboring gene uncharacterized LOC134484822 Neighboring gene RNA, U6 small nuclear 26 Neighboring gene parathyroid hormone Neighboring gene enolase 1, pseudogene 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    General gene information

    Markers

    Clone Names

    • MGC105916

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    BTB/POZ domain-containing protein 10
    Names
    BTB (POZ) domain containing 10
    K+ channel tetramerization protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014022.2NP_001014044.1  BTB/POZ domain-containing protein 10 isoform b

      See identical proteins and their annotated locations for NP_001014044.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6AQE4, Q5EAP0
      Conserved Domains (1) summary
      cd18385
      Location:117226
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    2. NM_001399401.1NP_001386330.1  BTB/POZ domain-containing protein 10 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6AQE4, F7EZ61
      Related
      ENSRNOP00000060287.2, ENSRNOT00000067170.4
      Conserved Domains (1) summary
      cd18385
      Location:165274
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    3. NM_001399402.1NP_001386331.1  BTB/POZ domain-containing protein 10 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6AQE4, F7EZ61
      Conserved Domains (1) summary
      cd18385
      Location:165274
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    4. NM_001399403.1NP_001386332.1  BTB/POZ domain-containing protein 10 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6AQE4, Q5EAP0
      Conserved Domains (1) summary
      cd18385
      Location:117226
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    5. NM_001399404.1NP_001386333.1  BTB/POZ domain-containing protein 10 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6AQE4, Q5EAP0
      Related
      ENSRNOP00000096128.1, ENSRNOT00000099504.2
      Conserved Domains (1) summary
      cd18385
      Location:117226
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      176865817..176923663 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039113416.2XP_038969344.1  BTB/POZ domain-containing protein 10 isoform X4

      UniProtKB/TrEMBL
      A0A8I6AQE4, Q5EAP0
      Conserved Domains (1) summary
      cd18385
      Location:117226
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    2. XM_017589192.2XP_017444681.1  BTB/POZ domain-containing protein 10 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AQE4, F7EZ61
      Conserved Domains (1) summary
      cd18385
      Location:165274
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    3. XM_039113392.2XP_038969320.1  BTB/POZ domain-containing protein 10 isoform X3

      UniProtKB/TrEMBL
      A0A0G2JZA0, A0A8I6AQE4
      Related
      ENSRNOP00000070965.1, ENSRNOT00000081767.3
      Conserved Domains (1) summary
      cd18385
      Location:154263
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    4. XM_039113386.2XP_038969314.1  BTB/POZ domain-containing protein 10 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AQE4, F7EZ61
      Conserved Domains (1) summary
      cd18385
      Location:165274
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    5. XM_006230038.5XP_006230100.1  BTB/POZ domain-containing protein 10 isoform X2

      See identical proteins and their annotated locations for XP_006230100.1

      UniProtKB/TrEMBL
      A0A8I6AQE4, F7EZ61
      Conserved Domains (1) summary
      cd18385
      Location:165274
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)
    6. XM_063262859.1XP_063118929.1  BTB/POZ domain-containing protein 10 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AQE4, F7EZ61
    7. XM_006230033.5XP_006230095.1  BTB/POZ domain-containing protein 10 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A2B2, A0A8I6AQE4
      Related
      ENSRNOP00000086484.1, ENSRNOT00000096757.2
      Conserved Domains (1) summary
      pfam16017
      Location:209438
      BTB_3; BTB/POZ domain
    8. XM_039113428.2XP_038969356.1  BTB/POZ domain-containing protein 10 isoform X5

      Conserved Domains (1) summary
      cd18385
      Location:173282
      BTB_POZ_BTBD10_GMRP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 10 (BTBD10)