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    Stfa2l2 stefin A2-like 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498087, updated on 27-Dec-2024

    Summary

    Symbol
    Stfa2l2provided by RGD
    Full Name
    stefin A2-like 2provided by RGD
    Primary source
    RGD:1560676
    See related
    EnsemblRapid:ENSRNOG00000076506 AllianceGenome:RGD:1560676
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Stfa2l3; RGD1560676
    Summary
    Predicted to enable cysteine-type endopeptidase inhibitor activity. Predicted to be located in cytoplasm. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 8.5), Lung (RPKM 8.5) and 3 other tissues See more
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    Genomic context

    See Stfa2l2 in Genome Data Viewer
    Location:
    11q22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (78003490..78005912)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (64498151..64500576)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (67451583..67454007)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene cystatin domain containing 4 Neighboring gene U6 spliceosomal RNA Neighboring gene stefin-2-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cysteine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    stefin A2-like 2; stefin-2
    Names
    stefin A2-like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430800.1NP_001417729.1  stefin A2-like 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A0A8I6GJV2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      78003490..78005912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006248415.5XP_006248477.2  stefin-2

      Related
      ENSRNOP00000091715.1, ENSRNOT00000098787.2
      Conserved Domains (1) summary
      pfam00031
      Location:1097
      Cystatin; Cystatin domain