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    CG12909 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36087, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12909provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033507
    Locus tag
    Dmel_CG12909
    See related
    AllianceGenome:FB:FBgn0033507
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12909
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and rRNA processing. Predicted to be active in nucleolus. Is expressed in several structures, including Malpighian tubule primordium; anterior endoderm; embryonic/larval midgut primordium; gut section; and larval somatic muscle cell. Orthologous to human LYAR (Ly1 antibody reactive). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12909 in Genome Data Viewer
    Location:
    47A1-47A1; 2-62 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10310113..10311143)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6197618..6198648)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene CAP Neighboring gene Ribonuclease Z Neighboring gene Odorant-binding protein 46a Neighboring gene Nidogen Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Combinatorial binding predicts spatio-temporal cis-regulatory activity. Zinzen RP, et al. Nature, 2009 Nov 5. PMID 19890324
    2. Dissection of Nidogen function in Drosophila reveals tissue-specific mechanisms of basement membrane assembly. Dai J, et al. PLoS Genet, 2018 Sep. PMID 30260959, Free PMC Article
    3. Mutations of the withered (whd) gene in Drosophila melanogaster confer hypersensitivity to oxidative stress and are lesions of the carnitine palmitoyltransferase I (CPT I) gene. Strub BR, et al. Genome, 2008 Jun. PMID 18521119
    4. The phospho-docking protein 14-3-3 regulates microtubule-associated proteins in oocytes including the chromosomal passenger Borealin. Repton C, et al. PLoS Genet, 2022 Jun. PMID 35666772, Free PMC Article
    5. Laser microdissection of sensory organ precursor cells of Drosophila microchaetes. Buffin E, et al. PLoS One, 2010 Feb 19. PMID 20174573, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12909-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10310113..10311143
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136729.4 → NP_610573.1  uncharacterized protein Dmel_CG12909 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610573.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0AP73, Q7K0D3
      Related
      FBpp0087437
      Conserved Domains (1) summary
      pfam08790
      Location:33 → 60
      zf-LYAR; LYAR-type C2HC zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K0D3 Q7K0D3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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