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    CG9123 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32462, updated on 4-Jan-2025

    Summary

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    Official Symbol
    CG9123provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030629
    Locus tag
    Dmel_CG9123
    See related
    AllianceGenome:FB:FBgn0030629
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9123
    Summary
    Predicted to enable protein kinase inhibitor activity. Predicted to be involved in cell population proliferation and maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be active in nucleolus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut; embryonic/larval midgut primordium; and larval muscle cell. Orthologous to human PAK1IP1 (PAK1 interacting protein 1). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See CG9123 in Genome Data Viewer
    Location:
    13B6-13B6; 1-50 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15340373..15342117, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15234406..15236150, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene discontinuous actin hexagon Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44998 Neighboring gene Histone deacetylase 6 Neighboring gene uncharacterized protein Neighboring gene pre-mRNA processing factor 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recent strong positive selection on Drosophila melanogaster HDAC6, a gene encoding a stress surveillance factor, as revealed by population genomic analysis. Svetec N, et al. Mol Biol Evol, 2009 Jul. PMID 19349642
    2. Excess of amino acid substitutions relative to polymorphism between X-linked duplications in Drosophila melanogaster. Thornton K, et al. Mol Biol Evol, 2005 Feb. PMID 15483321
    3. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article
    4. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein kinase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell population proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosome biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9123-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15340373..15342117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132790.3 → NP_573018.1  uncharacterized protein Dmel_CG9123 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573018.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C5I7K5, Q9VXW4
      Related
      FBpp0073836
      Conserved Domains (3) summary
      COG2319
      Location:60 → 294
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:50 → 85
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:49 → 295
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXW4 Q9VXW4

    Gene LinkOut

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