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    retm real-time [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33899, updated on 9-Dec-2024

    Summary

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    Official Symbol
    retmprovided by FlyBase
    Official Full Name
    real-timeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031814
    Locus tag
    Dmel_CG9528
    See related
    AllianceGenome:FB:FBgn0031814
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9528; Dmel\CG9528
    Summary
    Located in mitochondrion. Is expressed in adult head. Orthologous to several human genes including SEC14L5 (SEC14 like lipid binding 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See retm in Genome Data Viewer
    Location:
    26D4-26D5; 2-20 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6448464..6455929, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6448464..6455929, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Fic domain-containing protein Neighboring gene Acyl-CoA oxidase 3 Neighboring gene farjavit Neighboring gene Ring finger and CHY zinc finger domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel family of mitochondrial proteins is represented by the Drosophila genes slmo, preli-like and real-time. Dee CT, et al. Dev Genes Evol, 2005 May. PMID 15700158
    2. PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail. Jiang K, et al. PLoS Biol, 2016 Feb. PMID 26863604, Free PMC Article
    3. RNA editing in Drosophila melanogaster: New targets and functional consequences. Stapleton M, et al. RNA, 2006 Nov. PMID 17018572, Free PMC Article
    4. Drosophila glia: Few cell types and many conserved functions. Yildirim K, et al. Glia, 2019 Jan. PMID 30443934
    5. Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases. Marcogliese PC, et al. Cell Rep, 2022 Mar 15. PMID 35294868, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    real-time
    Names
    CG9528-PA
    CG9528-PB
    CG9528-PC
    retm-PA
    retm-PB
    retm-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6448464..6455929 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298743.1 → NP_001285672.1  real-time, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285672.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95U56, Q9VMD6
      UniProtKB/TrEMBL
      B5RIN0
      Conserved Domains (3) summary
      smart01100
      Location:222 → 268
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:293 → 456
      CRAL_TRIO; CRAL/TRIO domain
      pfam04707
      Location:17 → 173
      PRELI; PRELI-like family

    2. NM_135184.4 → NP_609028.2  real-time, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609028.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95U56, Q9VMD6
      UniProtKB/TrEMBL
      B5RIN0
      Related
      FBpp0078902
      Conserved Domains (3) summary
      smart01100
      Location:222 → 268
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:293 → 456
      CRAL_TRIO; CRAL/TRIO domain
      pfam04707
      Location:17 → 173
      PRELI; PRELI-like family

    3. NM_001273203.2 → NP_001260132.1  real-time, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260132.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PB50
      Conserved Domains (3) summary
      smart01100
      Location:222 → 268
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:293 → 456
      CRAL_TRIO; CRAL/TRIO domain
      pfam04707
      Location:17 → 173
      PRELI; PRELI-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B5RIN0 B5RIN0
    M9PB50 M9PB50
    Q9VMD6.2 Q9VMD6

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