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    CG4806 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37948, updated on 4-Jan-2025

    Summary

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    Official Symbol
    CG4806provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0260456
    Locus tag
    Dmel_CG4806
    See related
    AllianceGenome:FB:FBgn0260456
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg4806; Dmel\CG4806
    Old locus tag
    CG4806
    Summary
    Predicted to enable mRNA binding activity. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in alopecia, neurologic defects, and endocrinopathy syndrome. Orthologous to human RBM28 (RNA binding motif protein 28). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See CG4806 in Genome Data Viewer
    Location:
    60D13-60D13; 2-107 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24666158..24668343, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20553681..20555866, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene NADH dehydrogenase (ubiquinone) 19 kDa subunit Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Painting of fourth Neighboring gene Matrix metalloproteinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Painting of fourth in genus Drosophila suggests autosome-specific gene regulation. Larsson J, et al. Proc Natl Acad Sci U S A, 2004 Jun 29. PMID 15210994, Free PMC Article
    2. Painting of fourth and chromosome-wide regulation of the 4th chromosome in Drosophila melanogaster. Johansson AM, et al. EMBO J, 2007 May 2. PMID 17318176, Free PMC Article
    3. Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival. Okuda K, et al. iScience, 2022 Sep 16. PMID 36060064, Free PMC Article
    4. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article
    5. A cross-species approach for the identification of Drosophila male sterility genes. Ibaraki K, et al. G3 (Bethesda), 2021 Aug 7. PMID 34849808, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4806-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24666158..24668343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138111.4 → NP_611955.2  uncharacterized protein Dmel_CG4806 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611955.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5RJM2, Q9W124
      Related
      FBpp0072239
      Conserved Domains (4) summary
      COG0724
      Location:2 → 154
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12415
      Location:230 → 306
      RRM3_RBM28_like; RNA recognition motif 3 in RNA-binding protein 28 (RBM28) and similar proteins
      cd12416
      Location:379 → 468
      RRM4_RBM28_like; RNA recognition motif 4 in RNA-binding protein 28 (RBM28) and similar proteins
      cl17169
      Location:49 → 124
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T9I4 Q8T9I4
    Q9W124 Q9W124

    Gene LinkOut

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