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    Chst7 carbohydrate sulfotransferase 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 302302, updated on 27-Dec-2024

    Summary

    Official Symbol
    Chst7provided by RGD
    Official Full Name
    carbohydrate sulfotransferase 7provided by RGD
    Primary source
    RGD:1303028
    See related
    EnsemblRapid:ENSRNOG00000077798 AllianceGenome:RGD:1303028
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gn6st-4
    Summary
    Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity and chondroitin 6-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and chondroitin sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human CHST7 (carbohydrate sulfotransferase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 28.7), Brain (RPKM 28.3) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Chst7 in Genome Data Viewer
    Location:
    Xq11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (4949810..4986372, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (2396260..2432828, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (2623018..2657155, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene egl-9 family hypoxia-inducible factor 1, pseudogene 1 Neighboring gene solute carrier family 9 member A7 Neighboring gene actin, beta, pseudogene 7 Neighboring gene actin, beta, pseudogene 8 Neighboring gene regulator of chromosome condensation 1, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC124926

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables N-acetylglucosamine 6-O-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables N-acetylglucosamine 6-O-sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables chondroitin 6-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chondroitin 6-sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in N-acetylglucosamine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in N-acetylglucosamine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chondroitin sulfate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chondroitin sulfate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sulfur compound metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    carbohydrate sulfotransferase 7
    Names
    C6ST-2
    GST-5
    N-acetylglucosamine 6-O-sulfotransferase 1
    N-acetylglucosamine 6-O-sulfotransferase 4
    carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
    chondroitin 6-sulfotransferase 2
    chondroitin 6-sulfotransferase 7
    galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5
    glcNAc6ST-4
    NP_997483.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207600.2NP_997483.1  carbohydrate sulfotransferase 7 precursor

      See identical proteins and their annotated locations for NP_997483.1

      Status: PROVISIONAL

      Source sequence(s)
      BC111079
      UniProtKB/Swiss-Prot
      Q2TA65, Q6XQG8
      UniProtKB/TrEMBL
      A6JZU6
      Related
      ENSRNOP00000105160.1, ENSRNOT00000123023.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      4949810..4986372 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)