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    Defb49 defensin beta 49 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 641653, updated on 9-Dec-2024

    Summary

    Official Symbol
    Defb49provided by RGD
    Official Full Name
    defensin beta 49provided by RGD
    Primary source
    RGD:1560245
    See related
    EnsemblRapid:ENSRNOG00000039651 AllianceGenome:RGD:1560245
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. Orthologous to human DEFB133 (defensin beta 133 (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Defb49 in Genome Data Viewer
    Location:
    9q13
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (28329236..28333898, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (20832686..20837352, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (24445115..24451499, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094646 Neighboring gene cysteine-rich secretory protein 1 Neighboring gene defensin beta 18 Neighboring gene defensin beta 16 pseudogene Neighboring gene defensin beta 17

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    beta-defensin 133
    Names
    beta-defensin 49

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037527.2NP_001032616.1  beta-defensin 133 precursor

      See identical proteins and their annotated locations for NP_001032616.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      Q32ZF1
      Related
      ENSRNOP00000057532.1, ENSRNOT00000060805.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      28329236..28333898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)