Garem2 GRB2 associated regulator of MAPK1 subtype 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Garem2provided by RGD
Official Full Name: GRB2 associated regulator of MAPK1 subtype 2provided by RGD
Primary source: RGD:1597138
See related: EnsemblRapid:ENSRNOG00000048004 AllianceGenome:RGD:1597138
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam59b; Gareml
Summary: Orthologous to human GAREM2 (GRB2 associated regulator of MAPK1 subtype 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 14.3), Heart (RPKM 9.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 6q14

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (31949877..31961591, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (26228965..26255576, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (27631364..27643076, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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General protein information

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Preferred Names: GRB2-associated and regulator of MAPK protein 2

Names: GRB2 associated regulator of MAPK1, member 2; GRB2 associated, regulator of MAPK1-like; GRB2-associated and regulator of MAPK protein-like; family with sequence similarity 59, member B; protein FAM59B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191874.1 → NP_001178803.1 GRB2-associated and regulator of MAPK protein 2

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000006

UniProtKB/TrEMBL

M0RB26

Related

ENSRNOP00000066748.1, ENSRNOT00000074348.3

Conserved Domains (2) summary

cd09525
Location:811 → 877

SAM_GAREM; SAM domain of GAREM subfamily

pfam12736
Location:29 → 338

CABIT; Cell-cycle sustaining, positive selection,