U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RT1-T18 RT1 class Ib, locus T18 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 406194, updated on 27-Nov-2024

    Summary

    Go to the top of the page Help
    Symbol
    RT1-T18provided by RGD
    Full Name
    RT1 class Ib, locus T18provided by RGD
    Primary source
    RGD:1303092
    See related
    EnsemblRapid:ENSRNOG00000071227 AllianceGenome:RGD:1303092
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tla; H2-T3; H2-T18
    Expression
    Biased expression in Thymus (RPKM 548.0) and Spleen (RPKM 21.2) See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RT1-T18 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (2605478..2614543)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (2605261..2608909)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3113026..3114031)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene serine and arginine rich splicing factor 6, pseudogene 1 Neighboring gene class I gene fragment 2458 Neighboring gene RT1 class I, locus CE15, pseudogene 1 Neighboring gene RT1 class I, locus V1, pseudogene 1 Neighboring gene ribosomal protein S2, pseudogene 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Hyperconservation of the putative antigen recognition site of the MHC class I-b molecule TL in the subfamily Murinae: evidence that thymus leukemia antigen is an ancient mammalian gene. Davis BK, et al. J Immunol, 2002 Dec 15. PMID 12471122
    2. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, et al. Genome Res, 2004 Apr. PMID 15060004, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    RT1 class Ib, locus T18
    Names
    H-2 class I histocompatibility antigen, TLA(B) alpha chain-like
    MHC class Ib antigen
    TL antigen
    histocompatibility 2, T region locus 18
    histocompatibility 2, T region locus 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002821.1 → NP_001002821.1  RT1 class Ib, locus T18 precursor

      See identical proteins and their annotated locations for NP_001002821.1

      Status: VALIDATED

      Source sequence(s)
      BX883049
      UniProtKB/TrEMBL
      Q6MFZ7
      Related
      ENSRNOP00000098052.2, ENSRNOT00000120362.2
      Conserved Domains (2) summary
      cd07698
      Location:207 → 299
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:25 → 203
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      2605478..2614543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279362.1 → XP_063135432.1  RT1 class Ib, locus T18 isoform X1

    2. XM_063279363.1 → XP_063135433.1  RT1 class Ib, locus T18 isoform X1

    3. XM_063279365.1 → XP_063135435.1  RT1 class Ib, locus T18 isoform X2

      UniProtKB/TrEMBL
      Q6MFZ7

    4. XM_063279364.1 → XP_063135434.1  RT1 class Ib, locus T18 isoform X1

      Related
      ENSRNOP00000110418.1, ENSRNOT00000147531.1

    RNA

    1. XR_010060737.1 RNA Sequence

    2. XR_010060738.1 RNA Sequence

    3. XR_010060733.1 RNA Sequence

    4. XR_010060735.1 RNA Sequence

    5. XR_010060736.1 RNA Sequence

    6. XR_010060734.1 RNA Sequence

    7. XR_010060739.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools