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    C14h1orf146 similar to human chromosome 1 open reading frame 146 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689986, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C14h1orf146provided by RGD
    Official Full Name
    similar to human chromosome 1 open reading frame 146provided by RGD
    Primary source
    RGD:1586315
    See related
    EnsemblRapid:ENSRNOG00000074494 AllianceGenome:RGD:1586315
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in reciprocal meiotic recombination and synaptonemal complex assembly. Predicted to be active in chromosome. Orthologous to human C1orf146 (chromosome 1 open reading frame 146). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 136.1), Testes (RPKM 37.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See C14h1orf146 in Genome Data Viewer
    Location:
    14p22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (2375311..2395331, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (2230404..2250420, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (3247640..3288017, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene growth factor independent 1 transcriptional repressor Neighboring gene RNA polymerase II associated protein 2 Neighboring gene glomulin, FKBP associated protein Neighboring gene BTB domain containing 8 Neighboring gene uncharacterized LOC108352691 Neighboring gene lysophosphatidylcholine acyltransferase 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex. Ersland KM, et al. BMC Neurosci, 2013 Jul 11. PMID 23844656, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in reciprocal meiotic recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in reciprocal meiotic recombination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in synaptonemal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synaptonemal complex assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein C1orf146 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109563.2 → NP_001103033.1  uncharacterized protein C1orf146 homolog

      See identical proteins and their annotated locations for NP_001103033.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A0G2K7H7, A6KPJ1
      Conserved Domains (1) summary
      pfam15162
      Location:12 → 173
      DUF4580; Domain of unknown function (DUF4580)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      2375311..2395331 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008769942.4 → XP_008768164.1  uncharacterized protein C1orf146 homolog isoform X1

      See identical proteins and their annotated locations for XP_008768164.1

      UniProtKB/TrEMBL
      D4A8A9
      Conserved Domains (1) summary
      pfam15162
      Location:12 → 173
      DUF4580; Domain of unknown function (DUF4580)

    2. XM_006250573.5 → XP_006250635.1  uncharacterized protein C1orf146 homolog isoform X1

      See identical proteins and their annotated locations for XP_006250635.1

      UniProtKB/TrEMBL
      D4A8A9
      Conserved Domains (1) summary
      pfam15162
      Location:12 → 173
      DUF4580; Domain of unknown function (DUF4580)

    3. XM_063273647.1 → XP_063129717.1  uncharacterized protein C1orf146 homolog isoform X4

    4. XM_006250575.5 → XP_006250637.1  uncharacterized protein C1orf146 homolog isoform X1

      See identical proteins and their annotated locations for XP_006250637.1

      UniProtKB/TrEMBL
      D4A8A9
      Conserved Domains (1) summary
      pfam15162
      Location:12 → 173
      DUF4580; Domain of unknown function (DUF4580)

    5. XM_006250581.5 → XP_006250643.1  uncharacterized protein C1orf146 homolog isoform X3

      Conserved Domains (1) summary
      pfam15162
      Location:12 → 144
      DUF4580; Domain of unknown function (DUF4580)

    6. XM_006250576.5 → XP_006250638.1  uncharacterized protein C1orf146 homolog isoform X1

      See identical proteins and their annotated locations for XP_006250638.1

      UniProtKB/TrEMBL
      D4A8A9
      Conserved Domains (1) summary
      pfam15162
      Location:12 → 173
      DUF4580; Domain of unknown function (DUF4580)

    7. XM_006250574.5 → XP_006250636.1  uncharacterized protein C1orf146 homolog isoform X1

      See identical proteins and their annotated locations for XP_006250636.1

      UniProtKB/TrEMBL
      D4A8A9
      Conserved Domains (1) summary
      pfam15162
      Location:12 → 173
      DUF4580; Domain of unknown function (DUF4580)

    8. XM_006250572.5 → XP_006250634.1  uncharacterized protein C1orf146 homolog isoform X1

      See identical proteins and their annotated locations for XP_006250634.1

      UniProtKB/TrEMBL
      D4A8A9
      Conserved Domains (1) summary
      pfam15162
      Location:12 → 173
      DUF4580; Domain of unknown function (DUF4580)

    9. XM_063273648.1 → XP_063129718.1  uncharacterized protein C1orf146 homolog isoform X4

    10. XM_063273646.1 → XP_063129716.1  uncharacterized protein C1orf146 homolog isoform X2

      UniProtKB/TrEMBL
      A0A0G2K7H7, A6KPJ1

    11. XM_063273645.1 → XP_063129715.1  uncharacterized protein C1orf146 homolog isoform X2

      UniProtKB/TrEMBL
      A0A0G2K7H7, A6KPJ1

    12. XM_039092477.2 → XP_038948405.1  uncharacterized protein C1orf146 homolog isoform X1

      Related
      ENSRNOP00000106554.1, ENSRNOT00000156313.1
      Conserved Domains (1) summary
      pfam15162
      Location:12 → 173
      DUF4580; Domain of unknown function (DUF4580)
    Nucleotide Protein Strain
    Heading Accession and Version

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