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    Serpina1f serpin family A member 1F [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314406, updated on 9-Dec-2024

    Summary

    Official Symbol
    Serpina1fprovided by RGD
    Official Full Name
    serpin family A member 1Fprovided by RGD
    Primary source
    RGD:1307899
    See related
    EnsemblRapid:ENSRNOG00000037762 AllianceGenome:RGD:1307899
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307899
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in endoplasmic reticulum. Predicted to be active in extracellular space. Orthologous to human SERPINA2 (serpin family A member 2 (gene/pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 4.2) See more
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    Genomic context

    See Serpina1f in Genome Data Viewer
    Location:
    6q32
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (128585697..128591902, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (122820752..122827112, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (127564811..127571016, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene serpin family A member 6 Neighboring gene serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16 Neighboring gene serpin family A member 1F like 2 Neighboring gene serpin family A member 1F like 1 Neighboring gene serpin family A member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    alpha-1-antitrypsin 1-6
    Names
    serine (or cysteine) peptidase inhibitor, clade A, member 1F

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108054.1NP_001101524.1  alpha-1-antitrypsin 1-6 precursor

      See identical proteins and their annotated locations for NP_001101524.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473982
      UniProtKB/TrEMBL
      A6JEP1, D4A4R7
      Related
      ENSRNOP00000054139.2, ENSRNOT00000057322.4
      Conserved Domains (1) summary
      cl38926
      Location:47410
      serpin; SERine Proteinase INhibitors (serpin) family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      128585697..128591902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)