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    Ybey ybeY metalloendoribonuclease [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361822, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ybeyprovided by RGD
    Official Full Name
    ybeY metalloendoribonucleaseprovided by RGD
    Primary source
    RGD:1308722
    See related
    EnsemblRapid:ENSRNOG00000021365 AllianceGenome:RGD:1308722
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308722
    Summary
    Predicted to enable RNA endonuclease activity. Predicted to be involved in rRNA processing. Predicted to be located in mitochondrion and nucleus. Orthologous to human YBEY (ybeY metalloendoribonuclease). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 20.8), Lung (RPKM 18.1) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ybey in Genome Data Viewer
    Location:
    20p12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (12164678..12175150)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (12165192..12174713)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (12917111..12926587)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene lanosterol synthase Neighboring gene minichromosome maintenance complex component 3 associated protein Neighboring gene similar to human chromosome 21 open reading frame 58 Neighboring gene pericentrin Neighboring gene uncharacterized LOC134483886 Neighboring gene disco-interacting protein 2 homolog A Neighboring gene S100 calcium binding protein B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA endonuclease activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    endoribonuclease YbeY
    Names
    putative ribonuclease
    rRNA maturation factor homolog
    ybeY metallopeptidase

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001434636.1NP_001421565.1  endoribonuclease YbeY isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A6JKD1, D4A815
    2. NM_001434637.1NP_001421566.1  endoribonuclease YbeY isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      12164678..12175150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279233.1XP_063135303.1  endoribonuclease YbeY isoform X2

    2. XM_006256301.5XP_006256363.1  endoribonuclease YbeY isoform X1

      Conserved Domains (1) summary
      TIGR00043
      Location:35148
      TIGR00043; rRNA maturation RNase YbeY

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001108529.1: Suppressed sequence

      Description
      NM_001108529.1: This RefSeq was removed because currently there is insufficient support for the transcript.