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    cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 [ Danio rerio (zebrafish) ]

    Gene ID: 324238, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cstf1provided by ZNC
    Official Full Name
    cleavage stimulation factor, 3' pre-RNA, subunit 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2958
    See related
    Ensembl:ENSDARG00000044820 AllianceGenome:ZFIN:ZDB-GENE-030131-2958
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc22d10; zgc:66207; zgc:77560; wu:fc22d10; wu:fd16h09
    Summary
    Predicted to act upstream of or within mRNA 3'-end processing. Predicted to be part of mRNA cleavage stimulating factor complex. Orthologous to human CSTF1 (cleavage stimulation factor subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See cstf1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (27817301..27827533, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (27570127..27580359, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496702 Neighboring gene uncharacterized LOC137496653 Neighboring gene eukaryotic translation initiation factor 4 gamma, 3a Neighboring gene endothelin converting enzyme 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mRNA cleavage stimulating factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mRNA cleavage stimulating factor complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cleavage stimulation factor subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001328559.1 → NP_001315488.1  cleavage stimulation factor subunit 1

      Status: VALIDATED

      Source sequence(s)
      BX601648, EH556892, EH592404
      UniProtKB/TrEMBL
      A0A8M1P431, F1QFK9
      Related
      ENSDARP00000111131.1, ENSDART00000130800.4
      Conserved Domains (4) summary
      COG2319
      Location:104 → 428
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:100 → 424
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam16699
      Location:6 → 62
      CSTF1_dimer; Cleavage stimulation factor subunit 1, dimerization domain
      sd00039
      Location:116 → 171
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      27817301..27827533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_212670.1: Suppressed sequence

      Description
      NM_212670.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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