cdk5r2a cyclin dependent kinase 5, regulatory subunit 2a (p39) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cdk5r2aprovided by ZNC
Official Full Name: cyclin dependent kinase 5, regulatory subunit 2a (p39)provided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-22
See related: Ensembl:ENSDARG00000071011 AllianceGenome:ZFIN:ZDB-GENE-050417-22
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cdk5r2; fj48b05; wu:fj48b05; zgc:110126
Summary: Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity and protein kinase binding activity. Acts upstream of or within embryonic retina morphogenesis in camera-type eye and retina layer formation. Predicted to be part of protein kinase 5 complex. Predicted to be active in cytoplasm and growth cone. Orthologous to human CDK5R2 (cyclin dependent kinase 5 regulatory subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (13742959..13744681)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (13613522..13615244)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cyclin-dependent protein serine/threonine kinase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables cyclin-dependent protein serine/threonine kinase activator activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in axon guidance	IBA Inferred from Biological aspect of Ancestor more info
involved_in brain development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within embryonic retina morphogenesis in camera-type eye	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within embryonic retina morphogenesis in camera-type eye	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within retina layer formation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within retina layer formation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in growth cone	IBA Inferred from Biological aspect of Ancestor more info
part_of protein kinase 5 complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cyclin-dependent kinase 5 activator 2a

Names: cyclin-dependent kinase 5, regulatory subunit 2 (p39); p39

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.