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    jtb jumping translocation breakpoint [ Danio rerio (zebrafish) ]

    Gene ID: 560832, updated on 9-Dec-2024

    Summary

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    Official Symbol
    jtbprovided by ZNC
    Official Full Name
    jumping translocation breakpointprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-674
    See related
    Ensembl:ENSDARG00000070150 AllianceGenome:ZFIN:ZDB-GENE-060503-674
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-191i18.1
    Summary
    Predicted to be involved in mitotic cytokinesis. Predicted to be located in membrane. Predicted to be active in cytoplasm and midbody. Predicted to colocalize with centrosome and spindle. Orthologous to human JTB (jumping translocation breakpoint). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See jtb in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (42227444..42235993)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (42657963..42666556)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene nuclear transcription factor Y, gamma Neighboring gene potassium voltage-gated channel subfamily KQT member 4 Neighboring gene uncharacterized LOC137488549 Neighboring gene si:ch211-191i18.4 Neighboring gene si:ch211-191i18.2 Neighboring gene cocaine- and amphetamine-regulated transcript 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    colocalizes_with spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein JTB

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044944.1 → NP_001038409.1  protein JTB

      Status: PROVISIONAL

      Source sequence(s)
      BC095879
      UniProtKB/TrEMBL
      A0A8M1N9V6, Q1L897
      Related
      ENSDARP00000123066.1, ENSDART00000131574.3
      Conserved Domains (1) summary
      pfam05439
      Location:49 → 112
      JTB; Jumping translocation breakpoint protein (JTB)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      42227444..42235993
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159745.5 → XP_005159802.1  protein JTB isoform X1

      UniProtKB/TrEMBL
      A0A8M2B6J2, Q1L896
      Related
      ENSDARP00000114439.1, ENSDART00000135436.3
      Conserved Domains (1) summary
      pfam05439
      Location:49 → 154
      JTB; Jumping translocation breakpoint protein (JTB)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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