gstk1 glutathione S-transferase kappa 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gstk1provided by ZNC
Official Full Name: glutathione S-transferase kappa 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-298
See related: Ensembl:ENSDARG00000056510 Ensembl:ENSDARG00000093119 AllianceGenome:ZFIN:ZDB-GENE-040718-298
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92763
Summary: Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be active in mitochondrion and peroxisome. Orthologous to human GSTK1 (glutathione S-transferase kappa 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 16

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (31981296..32013934, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (32055175..32059919, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables glutathione peroxidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutathione peroxidase activity	IEA Inferred from Electronic Annotation more info
enables glutathione transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutathione transferase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glutathione metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within glutathione metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
is_active_in peroxisome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: glutathione S-transferase kappa 1

NP_001002560.1

EC 2.5.1.18

XP_005158401.1

EC 2.5.1.18

XP_021322619.2

EC 2.5.1.18

XP_068070042.1

EC 2.5.1.18

XP_068070043.1

EC 2.5.1.18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002560.1 → NP_001002560.1 glutathione S-transferase kappa 1

See identical proteins and their annotated locations for NP_001002560.1

Status: PROVISIONAL

Source sequence(s)

BC076240

UniProtKB/TrEMBL

A0A8M1N0N7, Q6DGU9

Related

ENSDARP00000035103.7, ENSDART00000030282.9

Conserved Domains (1) summary

cd03021
Location:6 → 214

DsbA_GSTK; DsbA family, Glutathione (GSH) S-transferase Kappa (GSTK) subfamily; GSTK is a member of the GST family of enzymes which catalyzes the transfer of the thiol of GSH to electrophilic substrates. It is specifically located in the mitochondria and ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007127.7 Reference GRCz11 Primary Assembly

Range

31981296..32013934 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021466944.2 → XP_021322619.2 glutathione S-transferase kappa 1 isoform X3

UniProtKB/TrEMBL

A0A8M9PN41

Related

ENSDARP00000116858.1, ENSDART00000148176.3
XM_068213942.1 → XP_068070043.1 glutathione S-transferase kappa 1 isoform X1
XM_068213941.1 → XP_068070042.1 glutathione S-transferase kappa 1 isoform X1
XM_005158344.5 → XP_005158401.1 glutathione S-transferase kappa 1 isoform X2

See identical proteins and their annotated locations for XP_005158401.1

UniProtKB/TrEMBL

A0A8M1N0N7, Q6DGU9

Conserved Domains (1) summary

cd03021
Location:6 → 214

DsbA_GSTK; DsbA family, Glutathione (GSH) S-transferase Kappa (GSTK) subfamily; GSTK is a member of the GST family of enzymes which catalyzes the transfer of the thiol of GSH to electrophilic substrates. It is specifically located in the mitochondria and ...