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    poc1a POC1 centriolar protein A [ Danio rerio (zebrafish) ]

    Gene ID: 406322, updated on 9-Dec-2024

    Summary

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    Official Symbol
    poc1aprovided by ZNC
    Official Full Name
    POC1 centriolar protein Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1993
    See related
    AllianceGenome:ZFIN:ZDB-GENE-040426-1993
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wdr51a; zgc:56055; wu:fl82d01
    Summary
    Predicted to be involved in cilium assembly. Predicted to act upstream of or within cell projection organization. Predicted to be active in centriole and ciliary basal body. Orthologous to human POC1A (POC1 centriolar protein A). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    See poc1a in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (241217..309420, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (279499..282922, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene si:ch1073-456m8.1 Neighboring gene dual specificity phosphatase 7 Neighboring gene aminolevulinate, delta-, synthase 1 Neighboring gene neuropeptide FF-amide peptide precursor like Neighboring gene solute carrier family 11 member 2 Neighboring gene methyltransferase 1, tRNA methylguanosine Neighboring gene si:ch211-159e12.5 Neighboring gene cytochrome P450, family 27, subfamily B, polypeptide 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A highly conserved Poc1 protein characterized in embryos of the hydrozoan Clytia hemisphaerica: localization and functional studies. Fourrage C, et al. PLoS One, 2010 Nov 16. PMID 21103375, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell projection organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    POC1 centriolar protein homolog A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213049.1 → NP_998214.1  POC1 centriolar protein homolog A

      See identical proteins and their annotated locations for NP_998214.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045888
      UniProtKB/Swiss-Prot
      Q7ZVF0
      Conserved Domains (3) summary
      COG2319
      Location:14 → 300
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:10 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:21 → 58
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      241217..309420 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7ZVF0.1 GenPept UniProtKB/Swiss-Prot:Q7ZVF0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.