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    mplkip M-phase specific PLK1 interacting protein [ Danio rerio (zebrafish) ]

    Gene ID: 100003564, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mplkipprovided by ZNC
    Official Full Name
    M-phase specific PLK1 interacting proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070912-182
    See related
    Ensembl:ENSDARG00000078986 AllianceGenome:ZFIN:ZDB-GENE-070912-182
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-202i17.3
    Summary
    Predicted to be active in centrosome; midbody; and nucleus. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 4. Orthologous to human MPLKIP (M-phase specific PLK1 interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See mplkip in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (21605547..21607822)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (21947485..21949760)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene AFG3-like AAA ATPase 2 Neighboring gene inhibin subunit beta Ab Neighboring gene v-ral simian leukemia viral oncogene homolog Ab (ras related) Neighboring gene zgc:55781

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    M-phase-specific PLK1-interacting protein
    Names
    TTD non-photosensitive 1 protein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001202486.1 → NP_001189415.1  M-phase-specific PLK1-interacting protein

      Status: VALIDATED

      Source sequence(s)
      CR786574
      UniProtKB/TrEMBL
      A0A8M1P1S5, B0V0W7
      Related
      ENSDARP00000101285.3, ENSDART00000112014.4
      Conserved Domains (2) summary
      pfam15502
      Location:29 → 171
      MPLKIP; M-phase-specific PLK1-interacting protein
      cl12078
      Location:123 → 164
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      21605547..21607822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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