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    pigs phosphatidylinositol glycan anchor biosynthesis, class S [ Danio rerio (zebrafish) ]

    Gene ID: 767675, updated on 9-Dec-2024

    Summary

    Official Symbol
    pigsprovided by ZNC
    Official Full Name
    phosphatidylinositol glycan anchor biosynthesis, class Sprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-436
    See related
    Ensembl:ENSDARG00000017813 AllianceGenome:ZFIN:ZDB-GENE-060929-436
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:152927
    Summary
    Predicted to be involved in attachment of GPI anchor to protein. Predicted to act upstream of or within GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 95. Orthologous to human PIGS (phosphatidylinositol glycan anchor biosynthesis class S). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See pigs in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (39583302..39604587, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (39538390..39552802, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene dynein, light chain, LC8-type 2b Neighboring gene serine and arginine rich splicing factor 1b Neighboring gene aldolase C, fructose-bisphosphate, b Neighboring gene ribosomal protein S6 kinase related b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC152927

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in attachment of GPI anchor to protein IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within attachment of GPI anchor to protein IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of GPI-anchor transamidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of GPI-anchor transamidase complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GPI transamidase component PIG-S

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076614.1NP_001070082.1  GPI transamidase component PIG-S

      See identical proteins and their annotated locations for NP_001070082.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124178
      UniProtKB/TrEMBL
      Q08CM2
      Related
      ENSDARP00000131639.1, ENSDART00000161516.2
      Conserved Domains (1) summary
      pfam10510
      Location:31557
      PIG-S; Phosphatidylinositol-glycan biosynthesis class S protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      39583302..39604587 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009295629.4XP_009293904.1  GPI transamidase component PIG-S isoform X2

      See identical proteins and their annotated locations for XP_009293904.1

      UniProtKB/TrEMBL
      A0A8M3B4Z0, I3ISB5
      Related
      ENSDARP00000125787.1, ENSDART00000151638.2
    2. XM_068215931.1XP_068072032.1  GPI transamidase component PIG-S isoform X1