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    rims2a regulating synaptic membrane exocytosis 2a [ Danio rerio (zebrafish) ]

    Gene ID: 393672, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rims2aprovided by ZNC
    Official Full Name
    regulating synaptic membrane exocytosis 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1656
    See related
    Ensembl:ENSDARG00000101606 AllianceGenome:ZFIN:ZDB-GENE-040426-1656
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rims2; zgc:73064
    Summary
    Predicted to enable metal ion binding activity and small GTPase binding activity. Predicted to act upstream of or within exocytosis and intracellular protein transport. Predicted to be located in membrane and synapse. Is expressed in nervous system and pancreatic system. Orthologous to human RIMS2 (regulating synaptic membrane exocytosis 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rims2a in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (44337082..44649686, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (44372880..44505183, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487970 Neighboring gene dihydropyrimidinase Neighboring gene dendrocyte expressed seven transmembrane protein Neighboring gene ddb1 and cul4 associated factor 13 Neighboring gene zgc:101716

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Analysis and functional evaluation of the hair-cell transcriptome. McDermott BM Jr, et al. Proc Natl Acad Sci U S A, 2007 Jul 10. PMID 17606911, Free PMC Article
    2. Expression profiling and functional characterization of the duplicated Oxr1b gene in zebrafish. Xu H, et al. Comp Biochem Physiol Part D Genomics Proteomics, 2021 Sep. PMID 34111665
    3. Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. Sundström G, et al. PLoS One, 2010 May 6. PMID 20463905, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC73064

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    regulating synaptic membrane exocytosis protein 2
    Names
    regulating synaptic membrane exocytosis 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      44337082..44649686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214248.1 → XP_068070349.1  regulating synaptic membrane exocytosis protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AIH2

    2. XM_021467012.2 → XP_021322687.2  regulating synaptic membrane exocytosis protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M3AIH2

    3. XM_068214246.1 → XP_068070347.1  regulating synaptic membrane exocytosis protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AIH2

    4. XM_021467015.2 → XP_021322690.1  regulating synaptic membrane exocytosis protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8M9PNB2
      Related
      ENSDARP00000140238.1, ENSDART00000170932.2
      Conserved Domains (1) summary
      cd04028
      Location:118 → 263
      C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_200699.1: Suppressed sequence

      Description
      NM_200699.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
    Nucleotide Protein Strain
    Heading Accession and Version

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